Obesity Studies

Acute Anti-Hyperglycaemic Activity of Five Traditional Medicinal Plants in High Fat Diet Induced Obese Rats.

Researchers investigated traditional medicinal plants as alternative treatments for diabetes mellitus, aiming to overcome the limitations of current anti-diabetic drugs.

Obesity Xanthium strumarium
Hannan J et al (2023).
Front Biosci (Schol Ed).
DOI:
10.31083/j.fbs1502005
PubMed:
37401506

Acacia nilotica stem bark extract ameliorates obesity, hyperlipidemia, and insulin resistance in a rat model of high fat diet-induced obesity.

The researchers studied the stem bark of () and its fractions in a high fat diet rat model to understand its protective effects.

Obesity Acacia nilotica
Khalaf SS et al (2023).
J Tradit Complement Med.
DOI:
10.1016/j.jtcme.2023.03.005
PubMed:
37396158

Brassica rapa L. prevents Western diet-induced obesity in C57BL/6 mice through its binding capacity of cholesterol and fat.

Researchers found that supplementing the diet of mice with Brassica rapa L. (B. rapa L.) reduced body weight gain, lipid accumulation, and increased excretion of cholesterol and triglycerides. This suggests that B. rapa L. could be a useful functional vegetable in combating obesity.

Obesity Brassica rapa
Tanaka Y et al (2023).
Biosci Biotechnol Biochem.
DOI:
10.1093/bbb/zbad086
PubMed:
37355784

Network pharmacology and multitarget analysis of Nigella sativa in the management of diabetes and obesity: a computational study.

Scientists identified potential compounds from black cumin that can inhibit protein targets and pathways associated with diabetes and obesity. Kaempferol was found to be the best binder for AKT1.

DiabetesObesity Nigella sativa
Saleem M et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2222837
PubMed:
37350443

Correction: Uncovering the effect of Moringa oleifera Lam. leaf addition to Fuzhuan Brick Tea on sensory properties, volatile profiles and anti-obesity activity.

This is a correction for a study on the impact of adding Lam. leaf to Fuzhuan Brick Tea. It discusses sensory properties, volatile profiles, and anti-obesity activity.

Obesity Moringa oleifera
Li X et al (2023).
Food Funct.
DOI:
10.1039/d3fo90057f
PubMed:
37341677

Chios mastiha essential oil exhibits antihypertensive, hypolipidemic and anti-obesity effects in metabolically unhealthy adults - a randomized controlled trial.

Chios Mastiha Essential Oil (CMEO) improved blood lipid profile, blood pressure, weight, body fat, and quality of life in individuals with abdominal obesity and metabolic abnormalities. It may have anti-obesity effects through inflammation and antioxidant modulation.

ObesityPhytochemistry Pistacia lentiscus
Gioxari A et al (2023).
Pharmacol Res.
DOI:
10.1016/j.phrs.2023.106821
PubMed:
37329633

Extra virgin coconut oil (Cocos nucifera L.) intake shows neurobehavioural and intestinal health effects in obesity-induced rats.

Researchers studied the effects of E-VCO on obese rats. E-VCO reduced energy intake and body weight gain, showed antidepressant effects, and improved gut health. It may have potential for treating obesity-related comorbidities.

GastroenterologyObesity Cocos nucifera
Araújo de Vasconcelos MH et al (2023).
Food Funct.
DOI:
10.1039/d3fo00850a
PubMed:
37318515

[Effects of Rosa roxburghii on insulin resistance in obese rats and its mechanisms].

Rosa roxburghii can improve insulin resistance in obese rats by reducing oxidative stress and increasing the expression of certain proteins and genes. This may be related to the PI3K/Akt2/GLUT4 signaling pathway.

Obesity Rosa roxburghii
Zhang SJ et al (2022).
Zhongguo Ying Yong Sheng Li Xue Za Zhi.
DOI:
10.12047/j.cjap.6328.2022.122
PubMed:
37308415
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