Rhodojaponin III-Loaded Chitosan Derivatives-Modified Solid Lipid Nanoparticles for Multimodal Antinociceptive Effects in vivo.

Researchers investigated the use of RJ-III, a bioactive compound found in a plant, in a drug delivery system to improve its release and pain-relieving effects.

Yang Q et al (2022).

Int J Nanomedicine.

DOI:

10.2147/IJN.S362443

PubMed:

35996527

The efficacy and toxicity of grayanoids as analgesics: A systematic review.

The researchers studied grayanoids, diterpenoids found in certain plants, commonly used to treat abdominal pain, headaches, and arthritis.

Yang J, Zhao J and Zhang J (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115581

PubMed:

35948141

Biological Functions of Dillenia pentagyna Roxb. Against Pain, Inflammation, Fever, Diarrhea, and Thrombosis: Evidenced From in vitro, in vivo, and Molecular Docking Study.

Sultana N et al (2022).

Front Nutr.

DOI:

10.3389/fnut.2022.911274

PubMed:

35903446

Evaluation of the effectiveness of Lactuca Sativa syrup in controlling pain after periodontal flap surgery: a split-mouth, randomized, double-blind placebo-controlled trial.

Researchers conducted a clinical trial to assess the pain-reducing effects of an herbal syrup as a complementary therapy after periodontal flap surgery.

Jafari H, Latifi SA and Bayani M (2022).

J Complement Integr Med.

DOI:

10.1515/jcim-2021-0190

PubMed:

35796290

Antinociceptive and anti-inflammatory effect of a standardized fraction of Oenothera rosea L'Hér. ex Aiton and its possible mechanism of action in mice.

Study investigated pain relief and reduction of inflammation by ethyl acetate fraction in mice, determining its mechanism. Relevant for developing potential treatments.

Vargas-Ruiz R et al (2022).

Avicenna J Phytomed.

DOI:

10.22038/AJP.2022.19616

PubMed:

35782768

Combining DNA and HPTLC profiles to differentiate a pain relief herb, Mallotus repandus, from plants sharing the same common name, "Kho-Khlan".

This study developed a method combining HPTLC and Bar-HRM analysis to differentiate between Mallotus repandus and two other plant species with the same common name. This technique can be used to accurately identify plant species, which is important for ensuring the safety and efficacy of medicinal formulas.

Thongkhao K et al (2022).

PLoS One.

DOI:

10.1371/journal.pone.0268680

PubMed:

35679267

Antinociceptive effect of ethanolic extract of Bauhinia brachycarpa Benth on neuropathic pain model induced by partial sciatic nerve ligation.

Chen YN et al (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115412

PubMed:

35640742

Polyphenolic Profile, Anti-Inflammatory and Anti-Nociceptive Activities of Some African Medicinal Plants.

Kagambega W et al (2022).

Plants (Basel).

DOI:

10.3390/plants11101377

PubMed:

35631802