Pain Studies

Intestinal anti-inflammatory and visceral analgesic effects of a Serpylli herba extract in an experimental model of irritable bowel syndrome in rats.

An extract from wild thyme improved pain and hypersensitivity in rats with IBS-like symptoms. It reduced inflammation, preserved gut barrier function, and inhibited mast cell activity. It may be a potential treatment for IBS.

Ruiz-Malagón AJ et al (2022).
Front Pharmacol.
PubMed:
36120292

Ceratonia siliqua leaves ethanol extracts exert anti-nociceptive and anti-inflammatory effects.

Ethanol extracts of L. leaves can alleviate pain by blocking pain signals. The plant also has various other benefits like neuroprotection, lowering blood pressure, and reducing inflammation.

Alqudah A et al (2022).
Heliyon.
PubMed:
36090223

The mixture of Agrimonia pilosa Ledeb. and Salvia miltiorrhiza Bunge. extract produces analgesic and anti-inflammatory effects in a collagen-induced arthritis mouse model.

The mixture extract from Ledeb (AP) and Bunge (SM) reduces pain and inflammation in arthritis through COX-1, COX-2, NF-κB, TNF-α, and IL-6 attenuation. Potential arthritis treatment.

Feng JH et al (2022).
Anim Cells Syst (Seoul).
PubMed:
36046031

In Vivo and In Silico Study of the Antinociceptive and Toxicological Effect of the Extracts of Petiveria alliacea L. Leaves.

This study investigated the pain-relieving properties of extracts from L. leaves and conducted a chemical analysis. The extracts reduced pain response and showed no toxicity, suggesting potential therapeutic use.

Cruz-Salomón KDC et al (2022).
Pharmaceuticals (Basel).
PubMed:
36015091

Investigation of the Antinociceptive Activity of the Hydroethanolic Extract of Junglas nigra Leaf by the Tail-Immersion and Formalin Pain Tests in Rats.

Researchers investigated the leaf of a medicinal plant used for inflammation relief. Findings could be relevant for treating inflammatory diseases.

Srebro D et al (2022).
Dose Response.
PubMed:
36003322