Pain Studies

Assessment of the anti-inflammatory and analgesic effects of Opuntia ficus indica L. Cladodes extract.

The study evaluated the anti-inflammatory and analgesic properties of L. extract in rats and mice. Results showed it reduced pain and inflammation, and chemical analysis identified 20 compounds with therapeutic effects. The extract could be a promising, affordable natural remedy for pain and inflammation in small animals, but more research is needed.

ImmunologyPain Opuntia ficus-indica
Ammam A et al (2023).
Libyan J Med.
DOI:
10.1080/19932820.2023.2275417
PubMed:
37905304

Design and Development of a Topical Nanogel Formulation Comprising of a Unani Medicinal Agent for the Management of Pain.

Scientists developed a nanogel delivery system for chamomile oil to treat pain. In vitro and in vivo studies showed enhanced skin penetration, improved pain threshold, and reduced skin irritation, making it a promising treatment for migraines.

Pain Matricaria chamomilla
Sah A et al (2023).
Gels.
DOI:
10.3390/gels9100794
PubMed:
37888367

Deciphering the Molecular Mechanism of Escin against Neuropathic Pain: A Network Pharmacology Study.

Escin, found in , has anti-inflammatory properties. This study uses network pharmacology, molecular docking, and molecular dynamics to understand how escin can help with neuropathic pain.

Pain Aesculus hippocastanum
Li X et al (2023).
Evid Based Complement Alternat Med.
DOI:
10.1155/2023/3734861
PubMed:
37876856

Phytochemical profiling and anti-inflammatory, analgesic activity of Ficus religiosa L. and molecular docking study against iNOS, TNF-α enzyme.

The study investigated the anti-inflammatory and analgesic properties of Ficus religiosa bark extract and the component quercetin. Both showed significant reduction in paw volume and pain symptoms, suggesting their potential use in treating pain and inflammation.

ImmunologyPainPhytochemistry Ficus religiosa
Ahmad S et al (2023).
Pak J Pharm Sci.
PubMed:
37869923

Ocimum basilicum essential oil in pacu Piaractus mesopotamicus: anesthetic efficacy, distribution, and depletion in different tissues.

Ocimum basilicum essential oil has potential as an anesthetic in aquaculture. A concentration of 300 mg L resulted in the fastest anesthesia and longest recovery period. Methyl chavicol and linalool were present in all tissue samples, but their concentrations decreased over time. The compounds were eliminated slower in the gills.

PainPhytochemistry Ocimum basilicum
Ventura AS et al (2023).
Vet Res Commun.
DOI:
10.1007/s11259-023-10225-8
PubMed:
37851315

Exploring the therapeutic potential of Prinsepia utilis Royle seed oil: A comprehensive study on chemical composition, physicochemical properties, anti-inflammatory, and analgesic activities.

Researchers studied the medicinal benefits of Prinsepia utilis (PU) Royle, a shrub from the Himalayan region used traditionally for treating conditions like pain and inflammation. Their findings may provide insights for potential therapeutic applications.

ImmunologyPainPhytochemistry Prinsepia utilis
Chauhan K et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117312
PubMed:
37844743

In Vivo, In Vitro and In Silico Study of Cucurbita moschata Flower Extract: A Promising Source of Natural Analgesic, Anti-Inflammatory, and Antibacterial Agents.

This study found that a flower extract has analgesic, anti-inflammatory, and antibacterial properties. It also identified potential therapeutic compounds and supports the traditional use of these flowers for pain and inflammation.

ImmunologyPain Cucurbita moschata
Hossain MR et al (2023).
Molecules.
DOI:
10.3390/molecules28186573
PubMed:
37764349

Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats.

Researchers investigated the medicinal properties of pineapple leaf in treating various health issues. Understanding these properties can help in developing new treatments for diarrhoea, inflammation, pain, bacterial infections, and oedema.

ImmunologyPainPhytochemistry Ananas comosus
Ugbogu EA et al (2023).
J Ethnopharmacol.
DOI:
10.1016/j.jep.2023.117224
PubMed:
37748634
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