Phytochemistry Studies

The basic chemical substances of total alkaloids of Uncaria rhynchophylla and their anti-neuroinflammatory activities.

Scientists identified new alkaloids in , which showed promising anti-neuroinflammatory effects by inhibiting NO production in microglial cells. Compounds , , , , , , and were particularly effective, with IC values of 5.87-76.78 M.

Qin JX et al (2024).
J Asian Nat Prod Res.
PubMed:
38373226

Critical review on anti-inflammation effects of saponins and their molecular mechanisms.

Saponins from plants and marine life show promise for anti-inflammatory therapies via molecular actions like NF-κB regulation. They shape the gut microbiome, impacting immune regulation and metabolic health, suggesting potential dietary interventions for chronic inflammation.

Wijesekara T, Luo J and Xu B (2024).
Phytother Res.
PubMed:
38372176

Study of the physicochemical characteristics, antimicrobial activity, and in vitro multiplication of wild blackberry species from the Peruvian highlands.

Study analyzed physicochemical composition, bioactive compounds, antimicrobial activity, and in vitro multiplication of wild blackberry species in Peruvian Andes. Results show potential for agricultural development, with R. floribundus, R. weberbaueri, and R. andicola species standing out. Management of genetic resources is supported.

Lapiz-Culqui YK et al (2024).
Sci Rep.
PubMed:
38365959