Phytochemistry Studies

The anti-inflammatory activity of flavonoids and alkaloids from Sophora flavescens alleviates psoriasiform lesions: Prenylation and methoxylation beneficially enhance bioactivity and skin targeting.

Researchers examined the anti-inflammatory effects of Sophora flavescens, finding that flavonoids had stronger inhibition of cytokine production than alkaloids, with prenylated flavanones offering the highest suppression. Prenylation and methoxylation of flavanones improved skin absorption and decreased epidermal thickness in mice, indicating potential for designing new treatments for psoriasis.

Lin CF et al (2024).
Phytother Res.
PubMed:
38358770

Phenolic composition and bioactivities of sea buckthorn (Hippophae rhamnoides L.) fruit and seeds: an unconventional source of natural antioxidants in North America.

Danielski R and Shahidi F (2024).
J Sci Food Agric.
PubMed:
38358042