Phytochemistry Studies

In-silico evaluation of natural alkaloids against the main protease and spike glycoprotein as potential therapeutic agents for SARS-CoV-2.

Scientists studied 102 alkaloids and found six from the lotus plant that can potentially treat COVID-19 by targeting the spike protein and protease of SARS-CoV-2, aiding drug discovery with minimal side effects.

Shah M et al (2024).
PLoS One.
PubMed:
38175855

Akebia saponin D attenuates allergic airway inflammation through AMPK activation.

Akebia saponin D (ASD), extracted from Dipsacus asper Wall, inhibits inflammation in lung cells and mice through AMPK activation, suggesting ASD as a potential treatment for allergic airway inflammation.

Xuan L et al (2024).
J Nat Med.
PubMed:
38175326

A comprehensive review on traditional applications, phytochemistry, pharmacology, and toxicology of Thymus serpyllum.

Thymus serpyllum, a traditional medicinal shrub from India, has potential for developing new drugs. Its essential oil has various pharmacological properties, but more studies are needed to validate its efficacy and explore its applications in medicine and food.

Salaria D et al (2023).
Indian J Pharmacol.
PubMed:
38174535

Morphological, phytochemical and genetic characterization of Centella asiatica accessions collected throughout Vietnam and Laos.

Scientists collected and characterized 26 pennywort accessions from Vietnam and Laos. They found that HUIB_CA20 and HUIB_CA27 were elite cultivars based on their high yield and phytochemical contents. Genetic diversity was also explored for breeding programs.

Truong HTH et al (2024).
Saudi J Biol Sci.
PubMed:
38173443

Anticancer activity of Curcuma aeroginosa essential oil and its nano-formulations: cytotoxicity, apoptosis and cell migration effects.

This study investigates the anticancer activity of Curcuma aeruginosa essential oil and its nano-formulations. Curcuma aeruginosa has potential in treating diseases and has various properties such as anti-HIV, hepatoprotective, antimicrobial, and anti-androgenic activities. Understanding its anticancer activity could have implications for cancer treatment.

Panyajai P et al (2024).
BMC Complement Med Ther.
PubMed:
38166788