Phytochemistry Studies

A Simple and Rapid High-Performance Liquid Chromatography Method for Preparation and Content Detection of the Mainly Numbing Taste Substances of Zanthoxylum bungeanum Maxim.

Researchers developed a method to obtain high-purity monomers of hydroxyl-α-sanshool and hydroxyl-β-sanshool, which are important indicators of Zanthoxylum bungeanum quality. Significant variation in these compounds was found among different types of Z. bungeanum.

Wang Z et al (2023).
J Chromatogr Sci.
PubMed:
37974461

Phytochemical analysis and anti-infective potential of fungal endophytes isolated from Nigella sativa seeds.

Study examines three endophytic fungi from Nigella sativa seeds, revealing potential antimicrobial properties against various pathogens. Molecular identification and chemical profiling of bioactive secondary metabolites support these findings. In-silico interactions also suggest effectiveness as antimicrobials.

Shady NH et al (2023).
BMC Microbiol.
PubMed:
37974074

[Effect of Continuous Cropping on the Physicochemical Properties, Microbial Activity, and Community Characteristics of the Rhizosphere Soil of Codonopsis pilosula].

Continuous cropping changes soil properties, microbial activity, and community characteristics, leading to increased organic carbon, phosphorus, nitrogen, and salt, while pH decreases. Bacterial diversity declines, but fungi diversity increases. Microbial community stability is disrupted. Bacterial community characteristics are influenced by phosphorus, potassium, carbon-nitrogen ratio, and soil respiration, while nitrogen, potassium, phosphorus, and soil respiration affect fungal community characteristics.

Yang Y et al (2023).
Huan Jing Ke Xue.
PubMed:
37973120

Exploring the phenolic profile, antibacterial, and antioxidant properties of walnut leaves (Juglans regia L.).

This study analyzed phenolic compounds in walnut leaves from northern Iraq. The compounds showed antibacterial and antioxidant properties, making them potential candidates for antioxidant drugs to treat oxidative stress-related diseases.

Altemimi AB et al (2023).
Food Sci Nutr.
PubMed:
37970415

Flavonoids contribute most to discriminating aged Guang Chenpi (Citrus reticulata 'Chachi') by spectrum-effect relationship analysis between LC-Q-Orbitrap/MS fingerprint and ameliorating spleen deficiency activity.

Researchers found that after 5 years of storage, aged Guang Chenpi, a Chinese herbal medicine, had increased flavonoid content and improved anti-spleen deficiency effects in mice. The study revealed that aged Guang Chenpi also regulated gut microbiota through specific flavonoids, highlighting the potential benefits of long storage time for herbal medicines.

Sun X et al (2023).
Food Sci Nutr.
PubMed:
37970411

Unraveling the serial glycosylation in the biosynthesis of steroidal saponins in the medicinal plant Paris polyphylla and their antifungal action.

Researchers discovered enzymes in a medicinal plant that produce bioactive compounds. They found that these enzymes are versatile and generated new compounds, including a potential antifungal agent.

Chen Y et al (2023).
Acta Pharm Sin B.
PubMed:
37969733

Steroidal Saponins from Solanum lyratum Thunb.

Researchers discovered four new steroidal compounds and isolated twenty known compounds from Solanum lyratum Thunb plants. Some of these compounds showed significant cytotoxic effects against human colon and hepatoma cells, offering potential for cancer treatment. This study also provides chemical markers to help differentiate Solanum plants.

Lai JX et al (2023).
Chem Biodivers.
PubMed:
37968243

One new prenylated flavonoid with cytotoxic activity from Epimedium brevicornu maxim.

Scientists discovered and identified four flavonoids from maxim leaves. One of them showed moderate cytotoxicity against Lewis Lung cancer cells, while the others had weak cytotoxic effects.

Zhang H et al (2023).
Nat Prod Res.
PubMed:
37966979