New dammarane-type triterpenoids from hydrolyzate of total Gynostemma pentaphyllum saponins with protein tyrosine phosphatase 1B inhibitory activity.
Researchers found that nine dammarane triterpenoids have significant inhibitory activity on protein tyrosine phosphatase 1B, indicating their potential as treatments for type 2 diabetes.
- Tan D et al (2023).
- J Enzyme Inhib Med Chem.
- PubMed:
- 37965892