Isolation of phenolic compound from Lawsonia inermis and its prediction as anti-diabetic agent using molecular docking and molecular dynamic simulation.

Scientists isolated and characterized a phenolic compound from the henna plant that has the potential as an anti-diabetic agent. The compound showed a high affinity for specific enzymes and was well-predicted in terms of skin permeability and distribution. Potential for new diabetes medication.

Musfiroh I et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2262595

PubMed:

37776010

New insights into the cytotoxic effects of Thymus vulgaris essential oil on the human triple-negative breast cancer cell line MDA-MB-231.

Thyme essential oil (EO) inhibited the growth and spread of triple-negative breast cancer cells. It induced apoptosis, increased oxidative stress, and activated Nrf2 pathway. Use of thyme EO may be beneficial for treating triple-negative breast cancer.

Benedetti S et al (2023).

Toxicol In Vitro.

DOI:

10.1016/j.tiv.2023.105705

PubMed:

37775061

Insights into the phenolic composition and in vitro bioactivity of cardoon capitulum: A nutraceutical-oriented valorization study.

Scientists studied the polyphenolic composition and bioactive properties of cardoon cultivars' capitulum constituents. Corolla and bracts of certain cultivars showed strong inhibitory effects on reactive substances, antihaemolytic activity, and antimicrobial potential, suggesting potential medical applications.

Mandim F et al (2023).

Food Chem.

DOI:

10.1016/j.foodchem.2023.137480

PubMed:

37774613

Phytochemical and Pharmacological Properties of a Traditional Herb, Strobilanthes Cusia (Nees) Kuntze.

Scientists found that using solvent-free microwave-assisted extraction (MAE) to extract bioactive components from Hom herbs yielded extracts with antioxidant, antibacterial, anti-inflammatory, cytotoxic, and anticancer properties. Distilled water, ethanol, and 50% ethanol were effective solvents for extracting these components. The extracts showed potential for treating bacterial infections and exhibited anticancer effects. Ethanol-extracted Hom showed high cytotoxicity.

Susawaengsup C et al (2023).

Mol Biotechnol.

DOI:

10.1007/s12033-023-00897-7

PubMed:

37773314

Improved sustained-release properties of ginger essential oil in a Pickering emulsion system incorporated in sodium alginate film and delayed postharvest senescence of mango fruits.

Zhang Y et al (2024).

Food Chem.

DOI:

10.1016/j.foodchem.2023.137534

PubMed:

37769562

Diversity and Isolation of Endophytic Fungi in Panax japonicus and Biotransformation Activity on Saponins.

Li P et al (2023).

Curr Pharm Biotechnol.

DOI:

10.2174/0113892010247700230919053439

PubMed:

37767797

Salvia rosmarinus Spenn. (Lamiaceae) Hydroalcoholic Extract: Phytochemical Analysis, Antioxidant Activity and In Vitro Evaluation of Fatty Acid Accumulation.

The study investigated the antioxidant activity of extracts from the rosemary plant. The extracts were found to contain beneficial compounds that could potentially reduce lipid accumulation in NAFLD.

Musolino V et al (2023).

Plants (Basel).

DOI:

10.3390/plants12183306

PubMed:

37765470

Exploring Carob (Ceratonia siliqua L.): A Comprehensive Assessment of Its Characteristics, Ethnomedicinal Uses, Phytochemical Aspects, and Pharmacological Activities.

Study: The carob tree has various medicinal properties and is used in traditional medicine. It contains compounds with antihypertensive, antidepressant, anti-obesity, and antihyperglycemic activities. This review explores the taxonomy, traditional uses, and biological properties of the carob tree (L.).

Dahmani W et al (2023).

Plants (Basel).

DOI:

10.3390/plants12183303

PubMed:

37765467