Molecular and Pharmacokinetic Aspects of the Acetylcholinesterase-Inhibitory Potential of the Oleanane-Type Triterpenes and Their Glycosides.

This study explores the acetylcholinesterase-inhibitory potential of various compounds found in the bark of (Combreatceae). Arjunetin and arjunglucoside I can cross the blood-brain barrier. These compounds show potential as cognition-enhancing agents and have a high binding energy. The kinetics of AChE inhibition were also tested.

Stępnik K, Kukula-Koch W and Płaziński W (2023).

Biomolecules.

DOI:

10.3390/biom13091357

PubMed:

37759757

New Esters from the Essential Oil of Dry Flowers of Elder (Sambucus nigra L.).

Raičević V et al (2023).

J Sci Food Agric.

DOI:

10.1002/jsfa.13012

PubMed:

37759401

Neuroprotective neolignan glycosides from the pseudobulbs of Bletilla striata.

Researchers discovered four new neolignan glycosides in Bletilla striata, which showed promising neuroprotective effects against glutamate-induced PC12 cell injury. These compounds are the first of their kind found in the genus Bletilla, indicating the potential of Bletilla striata as a source of anti-neurodegenerative agents.

Zhou M et al (2023).

Fitoterapia.

DOI:

10.1016/j.fitote.2023.105691

PubMed:

37757922

Antinociceptive effect of gelsenicine, principal toxic alkaloids of gelsemium, on prostaglandin E2-induced hyperalgesia in mice: Comparison with gelsemine and koumine.

Xu WB et al (2023).

Biochem Biophys Res Commun.

DOI:

10.1016/j.bbrc.2023.09.037

PubMed:

37757667

Effect of dielectric barrier discharge nonthermal plasma treatment on physicochemical, nutritional, and phytochemical quality attributes of pineapple [Ananas comosus (L.)] juice.

Pipliya S, Kumar S and Srivastav PP (2023).

J Food Sci.

DOI:

10.1111/1750-3841.16767

PubMed:

37755601

Phytochemical, antioxidant, and antibacterial activity of Moringa oleifera nanosuspension against peri-implantitis bacteria: An in vitro study.

Nugraha AP et al (2023).

J Oral Biol Craniofac Res.

DOI:

10.1016/j.jobcr.2023.09.004

PubMed:

37753264

Exogenous putrescine changes biochemical (antioxidant activity, polyphenol, flavonoid, and total phenol compounds) and essential oil constituents of Salvia officinalis L.

Zeynali R, Najafian S and Hosseinifarahi M (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202301043

PubMed:

37751472

Phytochemical characterization, anti-diarrhoeal, analgesic, anti-inflammatory activities and toxicity profile of Ananas comosus (L.) Merr (pineapple) leaf in albino rats.

Researchers investigated the medicinal properties of pineapple leaf in treating various health issues. Understanding these properties can help in developing new treatments for diarrhoea, inflammation, pain, bacterial infections, and oedema.

Ugbogu EA et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117224

PubMed:

37748634