Eucommia lignans alleviate the progression of diabetic nephropathy through mediating the AR/Nrf2/HO-1/AMPK axis in vivo and in vitro.
Eucommia lignans derived from Eucommia ulmoides Oliver have been found to inhibit the progression of diabetic nephropathy (DN) by reducing inflammation and improving renal function through the AR/Nrf2/HO-1/AMPK axis. This suggests that Eucommia lignans could be a potential treatment for DN.
- Huang Q et al (2023).
- Chin J Nat Med.
- PubMed:
- 37517819