Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.
New compounds with anti-inflammatory properties were found in the roots of L. These compounds showed even better effectiveness than a commonly used anti-inflammatory drug. Additionally, five of these compounds helped to enhance the effects of certain chemotherapeutic drugs against cervical cancer cells, including those resistant to paclitaxel. The combination of one particular compound and paclitaxel successfully promoted cancer cell death through a specific cellular pathway. This research could lead to new treatments for inflammatory diseases and cancer, offering hope for improved patient outcomes.
- Wan Q et al (2023).
- J Agric Food Chem.
- PubMed:
- 37392181