Phytochemistry Studies

Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.

New compounds with anti-inflammatory properties were found in the roots of L. These compounds showed even better effectiveness than a commonly used anti-inflammatory drug. Additionally, five of these compounds helped to enhance the effects of certain chemotherapeutic drugs against cervical cancer cells, including those resistant to paclitaxel. The combination of one particular compound and paclitaxel successfully promoted cancer cell death through a specific cellular pathway. This research could lead to new treatments for inflammatory diseases and cancer, offering hope for improved patient outcomes.

Wan Q et al (2023).
J Agric Food Chem.
PubMed:
37392181

Identification and quality evaluation of different processed products of Aconitum carmichaelii by ultra-high-performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry and ultra-high-performance liquid chromatography-tandem mass spectrometry.

Wei N et al (2023).
J Sep Sci.
PubMed:
37387561

Data regarding anti-quorum sensing and antimicrobial activity of Melaleuca alternifolia and Salvia sclarea essential oil against Pseudomonas aeruginosa.

Researchers investigated the antimicrobial and anti-quorum sensing properties of two essential oils against bacteria. They found sub-lethal concentrations that reduced virulence and pathogenic potential, affecting biofilm formation and gene expression.

Srivastava A et al (2023).
Data Brief.
PubMed:
37383790