Phytochemistry Studies

Neuroprotective and acetylcholinesterase inhibitory activities of alkaloids from Solanum lyratum Thunb.: An in vitro and in silico analyses.

Researchers extracted and isolated seven new alkaloids and 13 known alkaloids from the herb Solanum lyratum Thunb. They determined the structure of the new compounds and found that two of them, (-)-(7'S)-N-feruloyltyramine A and (+)-(7'R)-N-feruloyltyramine A, provided neuroprotective effects against cell damage and acetylcholinesterase inhibitory effects. The findings suggest that S. lyratum has potential as a source of new functional components for the pharmaceutical industry.

Chang Y et al (2023).
Phytochemistry.
PubMed:
36842735

Screening for α-glucosidase inhibitors from Selaginella uncinata based on the ligand fishing combined with ultra-high-performance liquid chromatography-quadrupole time-of-flight-tandem mass spectrometry.

Fan Z et al (2023).
Biomed Chromatogr.
PubMed:
36840461