Phytochemistry Studies

Structurally diverse lignans from Solanum lyratum: chemical evidence for their acetylcholinease inhibitory activity.

Researchers discovered two new lignans and 11 known lignan analogues from the Thumb. They separated two pairs of enantiomers and determined their structures using various methods. All compounds were tested for their acetylcholinesterase inhibitory activity. Two compounds showed clear AChE inhibition compared to the positive control. These findings suggest that the Thumb may potentially have therapeutic uses for treating diseases related to acetylcholinesterase dysfunction.

Zhang X et al (2022).
Nat Prod Res.
PubMed:
36345975

Development, validation and application of a gas chromatography method for the determination of dillapiole from Piper aduncum essential oil in skin permeation samples.

Braga Carneiro S et al (2023).
Biomed Chromatogr.
PubMed:
36342416