Phytochemistry, allelopathy and anticancer potentiality of Withania somnifera (L.) Dunal (Solanaceae).
- Ahmed HA and El-Darier SM (2022).
- Braz J Biol.
- PubMed:
- 36350950
Researchers discovered two new lignans and 11 known lignan analogues from the Thumb. They separated two pairs of enantiomers and determined their structures using various methods. All compounds were tested for their acetylcholinesterase inhibitory activity. Two compounds showed clear AChE inhibition compared to the positive control. These findings suggest that the Thumb may potentially have therapeutic uses for treating diseases related to acetylcholinesterase dysfunction.