Network Pharmacology and Experimental Study of Momordicine I and Momordicine II from Bitter Melon Saponins in Inhibiting Fat Accumulation.

Huang ST et al (2024).

Biomed Environ Sci.

DOI:

10.3967/bes2024.058

PubMed:

38843926

Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.

Tossers developed a supercritical fluid chromatography method to rapidly analyze and isolate benzylisoquinoline alkaloids in . This can aid in the development of new pharmaceuticals for gastrointestinal ailments.

Zwerger M et al (2024).

Planta Med.

DOI:

10.1055/a-2204-5686

PubMed:

38843792

Analyzing noncovalent interactions between notoginseng saponins and lysozyme by deposition scanning intensity fading MALDI-TOF mass spectrometry.

Improved IF-MALDI-MS method used to study binding of Panax notoginseng saponins with lysozyme. Results show binding affinity order and suggest hydrogen bonding role. Valuable for screening natural products for pharmacological activities.

Zhao X et al (2024).

J Mass Spectrom.

DOI:

10.1002/jms.5058

PubMed:

38842112

Antioxidant, antidiabetic, and anti-inflammatory activities of flavonoid-rich fractions of Solanum anguivi Lam. fruit: In vitro and ex vivo studies.

A study on flavonoids in fruits shows potential for treating diabetes due to antioxidant and anti-inflammatory properties, as well as inhibition of key enzymes. Fraction A is most effective. More research is needed for practical application.

Ojo AB and Adanlawo IG (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e31895

PubMed:

38841505

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a systematic review of in vitro studies.

Flavonoids in grape seed extract and cranberry show potential to impact Streptococcus mutans activity, could lead to new ways to combat oral bacteria.

Castellanos JS et al (2024).

BMC Oral Health.

DOI:

10.1186/s12903-024-04263-0

PubMed:

38840232

[Study on the total flavonoid content and antioxidant activity of Morus nigra Linn. from different origins in Xinjiang].

Scientists optimized a method to extract flavonoids from Morus nigra Linn. from different Xinjiang regions. This can help understand antioxidant properties and improve lab decisions.

Dawuti T et al (2024).

Wei Sheng Yan Jiu.

DOI:

10.19813/j.cnki.weishengyanjiu.2024.03.018

PubMed:

38839589

Phytochemical determination and mechanistic investigation of Polygala tenuifolia root (Yuanzhi) extract for bronchitis: UPLC-MS/MS analysis, network pharmacology and in vitro/in vivo evaluation.

Researchers studied the effectiveness of Polygala tenuifolia in treating bronchitis. Results suggest it may help relieve cough and remove phlegm. Further research needed on its molecular mechanisms.

Chen T et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118418

PubMed:

38838926

The antiangiogenic effect of total saponins of Panax japonicus C.A. Meyer in rheumatoid arthritis is mediated by targeting the HIF-1α/VEGF/ANG-1 axis.

Researchers extracted TSPJs from Panax japonicus C.A. Meyer, a traditional Chinese herbal medicine used to treat rheumatoid arthritis. The anti-inflammatory mechanism of TSPJs needs further investigation.

Guo X et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118422

PubMed:

38838922