Phytochemistry Studies

Chemometric guided isolation of new triterpenoid saponins as acetylcholinesterase inhibitors from seeds of Achyranthes bidentata Blume.

Researchers identified new compounds in Achyranthes bidentata seeds, potentially useful for treating various health conditions. Compound 23 showed promising acetylcholinesterase inhibitory activity, indicating potential therapeutic value. This study highlights the importance of using chemometric approaches for phytochemical exploration.

Puri S et al (2024).
Fitoterapia.
PubMed:
38537885

Dichroa febrifuga Lour.: A review of its botany, traditional use, phytochemistry, pharmacological activities, toxicology, and progress in reducing toxicity.

Scientists studied the toxic plant Dichroa febrifuga Lour., often used in traditional Chinese medicine as a treatment for malaria and parasitic diseases. Results may provide insights for future drug development.

Wang M et al (2024).
J Ethnopharmacol.
PubMed:
38537842

Cuscuta chinensis flavonoids alleviate ovarian damage in offspring female mice induced by BPA exposure during pregnancy by regulating the central carbon metabolism pathway.

Pregnant mice exposed to BPA can have reproductive damage in female offspring. CCFs mitigate this damage by regulating central carbon metabolism pathways and reducing oxidative stress. This study informs on potential BPA reproductive damage treatments.

Zhao Q et al (2024).
Ecotoxicol Environ Saf.
PubMed:
38537475

Advancing green extraction of bioactive compounds using deep eutectic solvent-based ultrasound-assisted matrix solid-phase dispersion: Application to UHPLC-PAD analysis of alkaloids and organic acids in Coptidis rhizoma.

Han M et al (2024).
Talanta.
PubMed:
38537350

New Analytical Approach to Quinolizidine Alkaloids and Their Assumed Biosynthesis Pathways in Lupin Seeds.

Scientists analyzed quinolizidine alkaloids in wild lupin seeds to understand their potential pharmacological uses. Method developed and pathway for alkaloid biosynthesis explored. Impact on future legume crop development.

Namdar D et al (2024).
Toxins (Basel).
PubMed:
38535829