Exploring the Mechanism of Brucea Javanica against Ovarian Cancer based on Network Pharmacology and the Influence of Luteolin on the PI3K/AKT Pathway.

Researchers studied the Chinese herbal medicine Brucea javanica for ovarian cancer treatment. Its effectiveness and mechanism were unknown, but if proven effective, it could offer new treatment options for this frequently diagnosed cancer.

Zhu J et al (2023).

Comb Chem High Throughput Screen.

DOI:

10.2174/1386207326666230627114111

PubMed:

37366364

Transcriptome profiling reveals the genes involved in tuberous root expansion in Pueraria (Pueraria montana var. thomsonii).

Xufeng X et al (2023).

BMC Plant Biol.

DOI:

10.1186/s12870-023-04303-x

PubMed:

37365513

Structural and Biochemical Characterization of Three Antimicrobial Peptides from Capsicum annuum L. var. annuum Leaves for Anti-Candida Use.

Cherene MB et al (2023).

Probiotics Antimicrob Proteins.

DOI:

10.1007/s12602-023-10112-3

PubMed:

37365421

Genome-wide discovery of di-nucleotide SSR markers based on whole genome re-sequencing data of Cicer arietinum L. and Cicer reticulatum Ladiz.

Sari D et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-37268-w

PubMed:

37365279

Tenuifolin in the prevention of Alzheimer's disease-like phenotypes: Investigation of the mechanisms from the perspectives of calpain system, ferroptosis, and apoptosis.

Li C et al (2023).

Phytother Res.

DOI:

10.1002/ptr.7930

PubMed:

37364988

Influence of exposure time, physicochemical properties, and plant transpiration on the uptake dynamics and translocation of pharmaceutical and personal care products in the aquatic macrophyte Typha latifolia.

Pérez DJ, Lombardero LR and Doucette WJ (2023).

Sci Total Environ.

DOI:

10.1016/j.scitotenv.2023.165107

PubMed:

37364828

A polysaccharide from Inula japonica showing in vivo antitumor activity by interacting with TLR-4, PD-1, and VEGF.

Researchers have purified a polysaccharide (IJP70-1) from Inula japonica flowers, a traditional medicinal plant. IJP70-1, with a molecular weight of 1.019 × 10 Da, has a unique structure composed of various sugar units. Studies using zebrafish models showed that IJP70-1 has promising antitumor activity. Interestingly, this activity is not due to direct toxicity, but rather through activating the immune system and inhibiting angiogenesis by interacting with specific proteins. These findings suggest that IJP70-1 has the potential to be developed into an effective anticancer agent.

Wang X et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.125555

PubMed:

37364807

A Double-Blind, Randomized, Placebo-Controlled Clinical Trial to Evaluate the Efficacy of Individualized Homeopathic Medicines in Pre-diabetes.

Pre-diabetes is a significant global health issue linked to stroke, heart diseases, and type-2 diabetes. It requires attention and intervention for prevention and management.

Guha N et al (2023).

Homeopathy.

DOI:

10.1055/s-0043-1769506

PubMed:

37364594