All Studies

In silico evidence implicating novel mechanisms of Prunella vulgaris L. as a potential botanical drug against COVID-19-associated acute kidney injury.

L, a Chinese herb, may help treat COVID-19-associated acute kidney injury. Key target genes inhibited by its compounds were identified, suggesting potential therapeutic benefits that require further study.

Yang XL et al (2023).
Front Pharmacol.
PubMed:
37274117

Potential Mechanisms of Imidacloprid-Induced Neurotoxicity in Adult Rats with Attempts on Protection Using Origanum majorana L. Oil/Extract: In Vivo and In Silico Studies.

Researchers investigated the impact of using essential oil or methanol extract from the aerial parts of Origanum majorana to protect rats against imidacloprid-induced neurotoxicity. They found that rats given OMO or OME along with imidacloprid showed less neurobehavioral and neuropathological damage, as well as improved levels of acetylcholine esterase, dopamine, serotonin, and gamma-aminobutyric acid in the brain. Both extracts had potent antioxidant, anti-inflammatory, and anti-apoptotic effects that helped protect against imidacloprid's effects. The study recommends daily intake of Origanum majorana to protect against neuroinflammatory stress and apoptosis induced by insecticides.

Hassanen EI et al (2023).
ACS Omega.
PubMed:
37273614

Nanoemulsion-Based System as a Novel and Promising Approach for Enhancing the Antimicrobial and Antitumoral Activity of Thymus vulgaris (L.) Oil in Human Hepatocellular Carcinoma Cells.

Nasra S, Meghani N and Kumar A (2023).
Appl Biochem Biotechnol.
PubMed:
37273096