All Studies

Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis.

Baicalin, a compound found in certain plants, has shown potential in improving polycystic ovary syndrome (PCOS), a hormonal and metabolic disorder in women.

Xu X et al (2023).
Pharm Biol.
PubMed:
37272921

Baicalin Reduces Renal Inflammation in Mesangial Proliferative Glomerulonephritis through Activation of Nrf2/ARE and PI3K/AKT Pathways.

Baicalin, found in Scutellaria baicalensis Georgi plant, has been shown to have kidney-protective properties. However, its impact on mesangial proliferative glomerulonephritis (MPGN) is not well understood. This study aimed to explore the effect of Baicalin on MPGN and uncover the mechanisms involved. By understanding how Baicalin affects MPGN, we can potentially develop new therapies for this prevalent form of primary glomerulonephritis.

Ning X et al (2023).
Discov Med.
PubMed:
37272104

Antidepressant effects of p-coumaric acid isolated from Vaccinium bracteatum leaves extract on chronic restraint stress mouse model and antagonism of serotonin 6 receptor in vitro.

Researchers investigated the effects of p-coumaric acid (CA) on chronic restraint stress (CRS)-induced immobility and serotonin (5-HT) receptor activity in mice. CA is the main active component of Vaccinium bracteatum Thunb. leaves, which are used in traditional medicine to treat various biological diseases. The study found that CA reduced CRS-induced immobility and increased 5-HT receptor activity, suggesting a potential therapeutic use in stress-related disorders.

Oh DR et al (2023).
Phytomedicine.
PubMed:
37270968