All Studies

An overview of natural products that modulate the expression of non-coding RNAs involved in oxidative stress and inflammation-associated disorders.

This review discusses the role of oxidative stress and inflammation in various diseases and highlights natural products that target non-coding RNAs to combat these disorders. Several natural products, including Baicalein, Curcumin, and Resveratrol, are effective in controlling oxidative stress and inflammation. Other compounds, such as Peppermint and Gingerol, show potential in treating these disorders but their effect on non-coding RNAs is unknown. Further research in this area will be valuable in developing natural compounds for therapy.

Ngum JA et al (2023).
Front Pharmacol.
PubMed:
37168992

Pulsatilla chinensis saponins ameliorated murine depression by inhibiting intestinal inflammation mediated IDO1 overexpression and rebalancing tryptophan metabolism.

Depression may be linked with inflammatory bowel disease (IBD). Researchers have found that intestinal inflammation might be a contributing factor to depression, but the exact cause is unknown. This suggests that new treatments for depression targeting the gut may be necessary.

Wang T et al (2023).
Phytomedicine.
PubMed:
37167824

Piperlongumine treatment impacts heart and liver development and causes developmental delay in zebrafish (Danio rerio) embryos.

Piperlongumine (PL) and piperine (PP) are alkaloids with anti-cancer potential. PL is highly toxic and affects heart development, while PP is safe. Careful strategies are needed when developing PL as a medicine.

Jeon HJ et al (2023).
Ecotoxicol Environ Saf.
PubMed:
37167734