In silico study of potential SARS-CoV-2 antagonist from Clitoria ternatea.

Researchers used a computer-based approach to identify natural compounds that may inhibit a viral protein, offering a potential avenue for developing new antiviral drugs. (33 characters)

Chun CY et al (2023).

Int J Health Sci (Qassim).

PubMed:

37151745

Lysionotin exerts antinociceptive effects in various models of nociception induction.

Lysionotin, a natural flavonoid from the plant Maxim, was studied for its pain-relieving properties. It showed potential as an analgesic, indicating possible use as a treatment for pain-related conditions.

Alqudah A et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e15619

PubMed:

37151635

Chemical Composition of Essential Oils from Nepeta transcaucasica Grossh. and Nepeta cataria L. Cultivated in Bulgaria and Their Antimicrobial and Antioxidant Activity.

Mollova S et al (2023).

ACS Omega.

DOI:

10.1021/acsomega.3c00704

PubMed:

37151483

Phylogeography of cultivated and wild ophiopogon japonicus based on chloroplast DNA: exploration of the origin and sustainable cultivation.

Zhao LY et al (2023).

BMC Plant Biol.

DOI:

10.1186/s12870-023-04247-2

PubMed:

37150815

Biochemometry identifies suppressors of pro-inflammatory gene expression in Pterocarpus santalinus heartwood.

Zwirchmayr J et al (2023).

Phytochemistry.

DOI:

10.1016/j.phytochem.2023.113709

PubMed:

37150433

Natural antioxidant formula ameliorates lipopolysaccharide-induced impairment of hippocampal neurogenesis and contextual fear memory through suppression of neuroinflammation in rats.

A natural antioxidant formula (NAF) composed of several beneficial compounds was given to rats in this study, who were also induced with lipopolysaccharide (LPS)-induced cognitive dysfunction. The NAF decreased inflammation in the brain and increased the number of neural progenitor cells, ultimately ameliorating the detrimental effects on neurogenesis and fear memory caused by LPS-induced inflammation. These findings suggest that NAF could be utilized to prevent neuroinflammation, which is thought to contribute to cognitive dysfunction.

Zeng W et al (2023).

J Chem Neuroanat.

DOI:

10.1016/j.jchemneu.2023.102285

PubMed:

37150363

Integrated analysis of topoisomerase I inhibitors from flavonoids of Scutellaria baicalensis Georgi using bioaffinity ultrafiltration UPLC-TripleTOF MS/MS, molecular docking and target-based multiple complex networks.

Tan N et al (2023).

Fitoterapia.

DOI:

10.1016/j.fitote.2023.105525

PubMed:

37150329

Dietary flaxseed (Linum usitatissimum) oil supplementation affects growth, oxidative stress, immune response, and diseases resistance in rainbow trout (Oncorhynchusmykiss).

Abdalla Salem MO et al (2023).

Fish Shellfish Immunol.

DOI:

10.1016/j.fsi.2023.108798

PubMed:

37150237