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Synaptoporin and parathyroid hormone 2 as markers of multimodal inputs to the auditory brainstem.

Researchers investigated the distribution of the synaptic vesicle protein synaptoporin in the mouse brainstem. They found region-specific differences in its accumulation, with higher levels in areas known to receive extra-auditory inputs. They also identified synaptoporin-positive synapses in the auditory system and traced their origin to the medial paralemniscal nucleus, which uses parathyroid hormone 2 as a transmitter. The study suggests that different inputs work together in the superior olivary complex.

Reuss S et al (2023).
J Chem Neuroanat.
PubMed:
36958466