All Studies

An Analysis of the Toxicity, Antioxidant, and Anti-Cancer Activity of Cinnamon Silver Nanoparticles in Comparison with Extracts and Fractions of Cinnamomum Cassia at Normal and Cancer Cell Levels.

El-Baz YG et al (2023).
Nanomaterials (Basel).
PubMed:
36903823

The Protective Effect of (-)-Tetrahydroalstonine against OGD/R-Induced Neuronal Injury via Autophagy Regulation.

Researchers isolated (-)-Tetrahydroalstonine (THA) and studied its effect on protecting neurons from oxygen-glucose deprivation/re-oxygenation (OGD/R)-induced damage. They pre-treated primary cortical neurons with THA and found it increased cell viability. THA also ameliorated autophagic activity and lysosomal dysfunction, which were present at the early stage of OGD/R. Additionally, THA activated the Akt/mTOR pathway, which was suppressed after OGD/R induction. This study suggests that THA exhibits promising neuroprotective effects against OGD/R-induced neuronal injury through autophagy regulation via the Akt/mTOR pathway.

Liao Y et al (2023).
Molecules.
PubMed:
36903613