Biomolecular Screening of Pimpinella anisum L. for Antioxidant and Anticholinesterase Activity in Mice Brain.

This study investigated the antioxidant and anti-amnesic activities of L. plant. Aqueous extract of dried seeds was fractionated and the active fraction (P.aAF) was analyzed. Behavioral and biochemical studies on mice showed significant results, including an increase in inflexion ratio and reduction in MDA and AChE levels, as well as promotion of CAT, SOD, and GSH levels in the brain. The LD for P.aAF was calculated as 95 mg/Kg/p.o. The findings suggest that the plant's oxadiazole compounds contribute to its beneficial effects.

Mushtaq A et al (2023).

Molecules.

DOI:

10.3390/molecules28052217

PubMed:

36903462

Two New 4-Hydroxy-2-pyridone Alkaloids with Antimicrobial and Cytotoxic Activities from Arthrinium sp. GZWMJZ-606 Endophytic with Houttuynia cordata Thunb.

Yin Y et al (2023).

Molecules.

DOI:

10.3390/molecules28052192

PubMed:

36903438

Two Ferulic Acid Derivatives Inhibit Neuroinflammatory Response in Human HMC3 Microglial Cells via NF-κB Signaling Pathway.

Scientists investigated the potential of two compounds from a plant extract in reducing inflammation related to neurodegenerative diseases. Using a human microglial cell model, they found that trans-ferulic acid and methyl ferulate significantly reduced the production of inflammatory mediators and increased levels of an anti-inflammatory factor. Additionally, the compounds inhibited the activation of a signaling pathway involved in inflammation. These findings suggest that the compounds could be useful in treating neuroinflammatory diseases.

Li PL et al (2023).

Molecules.

DOI:

10.3390/molecules28052080

PubMed:

36903325

Chitosan Spraying Enhances the Growth, Photosynthesis, and Resistance of Continuous Pinellia ternata and Promotes Its Yield and Quality.

Chen F et al (2023).

Molecules.

DOI:

10.3390/molecules28052053

PubMed:

36903297

Flavonoids from the Roots of Sophora flavescens and Their Potential Anti-Inflammatory and Antiproliferative Activities.

Yang YF et al (2023).

Molecules.

DOI:

10.3390/molecules28052048

PubMed:

36903293

Potential Anticancer Activity of Juniperus procera and Molecular Docking Models of Active Proteins in Cancer Cells.

Alhayyani S et al (2023).

Molecules.

DOI:

10.3390/molecules28052041

PubMed:

36903287

Ultrasound-Assisted Extraction of Total Phenolic Compounds and Antioxidant Activity Evaluation from Oregano (Origanum vulgare ssp. hirtum) Using Response Surface Methodology and Identification of Specific Phenolic Compounds with HPLC-PDA and Q-TOF-MS/MS.

Michalaki A et al (2023).

Molecules.

DOI:

10.3390/molecules28052033

PubMed:

36903279

Enhancing the Antimicrobial Effect of Ozone with Mentha piperita Essential Oil.

Floare AD et al (2023).

Molecules.

DOI:

10.3390/molecules28052032

PubMed:

36903277