All Studies

Hemi-synthesis of novel chiral benzodiazepine derivatives from Eucalyptus citriodora essential oil: 2D NMR experiments and differential scanning calorimetry study of diastereoisomers.

Cherfaoui B et al (2023).
Nat Prod Res.
PubMed:
36890766

Trihydroxy piperlongumine protects aluminium induced neurotoxicity in zebrafish: Behavioral and biochemical approach.

The study investigated the use of trihydroxy piperlongumine (THPL) as an antioxidant therapy for aluminium (Al) induced neurotoxicity in zebrafish. Fish exposed to Al showed increased oxidative stress, altered behavior and anxiety comorbid with depression. THPL effectively reduced free radicals and lipid peroxidation caused by Al and improved behavior deficits and anxiety-like behavior in adult fish. THPL also reduced the histological alterations caused by Al exposure. These results indicate that THPL is a promising candidate for treating Al-induced neurodegeneration.

Haridevamuthu B et al (2023).
Comp Biochem Physiol C Toxicol Pharmacol.
PubMed:
36889534