Encapsulation of Cymbopogon khasiana × Cymbopogon pendulus Essential Oil (CKP-25) in Chitosan Nanoemulsion as a Green and Novel Strategy for Mitigation of Fungal Association and Aflatoxin B(1) Contamination in Food System.

Prasad J et al (2023).

Foods.

DOI:

10.3390/foods12040722

PubMed:

36832806

Gastrodin Improves Cognitive Dysfunction in REM Sleep-Deprived Rats by Regulating TLR4/NF-κB and Wnt/β-Catenin Signaling Pathways.

Gastrodin, previously shown to improve cerebral ischemia-reperfusion and hypoperfusion injury and cognitive deficit in Alzheimer's disease, was administered orally to rats for 7 days to examine its effects on REM sleep deprivation. Results showed that gastrodin improved sleep disturbance, cognitive deficits, and neuron damage in the hippocampus and cerebral cortex. It did so by regulating the TLR4/NF-κB and Wnt/β-catenin signaling pathways. Gastrodin shows potential as a treatment for REM sleep deprivation.

Liu B et al (2023).

Brain Sci.

DOI:

10.3390/brainsci13020179

PubMed:

36831722

Molecular Screening of Bioactive Compounds of Garlic for Therapeutic Effects against COVID-19.

Researchers conducted a study to discover potential antiviral compounds from a natural plant source, screening 25 phytocompounds against the drug target 3CL protease by CB-dock. The best five compounds were Allicin, Diallyl Sulfide, Diallyl Disulfide, Diallyl Trisulfide, Ajoene, and Levamisole, which showed themselves as hit compounds. Further refining by screening filters represented Levamisole as a lead compound that may potentially treat SARS-CoV-2. However, more research must be done before determining their medicinal use.

Ashraf H et al (2023).

Biomedicines.

DOI:

10.3390/biomedicines11020643

PubMed:

36831179

Anti-Inflammatory Therapeutic Mechanisms of Natural Products: Insight from Rosemary Diterpenes, Carnosic Acid and Carnosol.

Habtemariam S et al (2023).

Biomedicines.

DOI:

10.3390/biomedicines11020545

PubMed:

36831081

Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.

Yang Y et al (2023).

Biomedicines.

DOI:

10.3390/biomedicines11020464

PubMed:

36831001

The Assessment of Antimicrobial and Anti-Biofilm Activity of Essential Oils against Staphylococcus aureus Strains.

Ersanli C et al (2023).

Antibiotics (Basel).

DOI:

10.3390/antibiotics12020384

PubMed:

36830295

Inhibitory Activity of Essential Oils of Mentha spicata and Eucalyptus globulus on Biofilms of Streptococcus mutans in an In Vitro Model.

Landeo-Villanueva GE et al (2023).

Antibiotics (Basel).

DOI:

10.3390/antibiotics12020369

PubMed:

36830281

Parasiticides: Weapons for Controlling Microbial Vector-Borne Diseases in Veterinary Medicine; The Potential of Ethnobotanic/Phytoparasiticides: An Asset to One Health.

Carvalho da Silva R et al (2023).

Antibiotics (Basel).

DOI:

10.3390/antibiotics12020341

PubMed:

36830252