All Studies

Angelica sinensis polysaccharides promote extramedullary stress erythropoiesis via ameliorating splenic glycolysis and EPO/STAT5 signaling-regulated macrophages.

Angelica sinensis polysaccharides (ASP) protect against anemia induced by chemotherapy, promote extramedullary erythropoiesis, and improve glycolysis via PI3K/Akt/HIF2α signaling. ASP enhances splenic macrophage activity, erythroid progenitor expansion, and erythroid differentiation, making it a promising treatment for stress anemia.

Sun N et al (2024).
J Mol Histol.
PubMed:
38969952

Anticancer efficacy of biosynthesized silver nanoparticles loaded with recombinant truncated parasporin-2 protein.

Researchers developed a novel nanotoxin using biosynthesized silver nanoparticles loaded with a toxin that selectively destroys cancer cells. This approach shows promise as a more effective and less harmful alternative to traditional cancer treatments.

Srisaisap M and Boonserm P (2024).
Sci Rep.
PubMed:
38969695

Efficacy of soothing cream gel in the range of motion and chronic pain at the shoulder and elbow: protocol of a double-blinded, randomised, placebo-controlled trial.

SCG cream gel may improve range of motion and chronic pain in shoulder and elbow, reducing the need for traditional treatments with undesirable side effects. Consider using SCG as an alternative therapy for upper limb problems.

Lo CW et al (2024).
BMJ Open.
PubMed:
38969378

Cannabidiol and Neurodegeneration: From Molecular Mechanisms to Clinical Benefits.

Researchers studied the role of cannabidiol (CBD) in treating neurodegenerative disorders through its antioxidant, anti-inflammatory, and neuroprotective properties. CBD shows promise in inhibiting protein aggregation, free radicals, and neuroinflammation, making it a potential therapeutic option for conditions like Alzheimer's and Parkinson's.

Jha SK et al (2024).
Ageing Res Rev.
PubMed:
38969143

Passion fruit HD-ZIP genes: Characterization, expression variance, and overexpression PeHB31 enhanced drought tolerance via lignin pathway.

Researchers identified and studied 34 HD-ZIP genes in passion fruit, finding PeHB31 enhances drought tolerance in transgenic plants by increasing lignin content. This could lead to improved understanding of lignin biosynthesis control mechanisms.

Ma F et al (2024).
Int J Biol Macromol.
PubMed:
38969043

Centipeda minima and 6-O-angeloylplenolin enhance the efficacy of immune checkpoint inhibitors in non-small cell lung cancer.

Chemotherapy drugs like cisplatin, gemcitabine, and pemetrexed boost immune checkpoint inhibitor efficacy in lung cancer, but low response rates and side effects hinder widespread use.

Wang M et al (2024).
Phytomedicine.
PubMed:
38968790

Piperine induces autophagy of colon cancer cells: Dual modulation of AKT/mTOR signaling pathway and ROS production.

Piperine, from black and long pepper, shows promise as an anticancer agent for colorectal cancer. Further research needed to understand its molecular mechanisms for potential use in treatment.

Xia J et al (2024).
Biochem Biophys Res Commun.
PubMed:
38968770

Structural and Functional Characterization of New Lipid Transfer Proteins with Chitin-Binding Properties: Insights from Protein Structure Prediction, Molecular Docking, and Antifungal Activity.

Scientists extracted and analyzed chitin-binding peptides from seeds to develop new antifungal agents. Peptides inhibited growth of certain fungi with low toxicity, showing potential for novel antifungal compounds.

Gonçalves GR et al (2024).
Biochemistry.
PubMed:
38968244