Urtica dioica agglutinin (UDA) as a potential candidate for inhibition of SARS-CoV-2 Omicron variants: In silico prediction and experimental validation.

Researchers studied the effectiveness of a plant-derived protein called Urtica dioica agglutinin (UDA) in blocking the Receptor Binding Domain (RBD) of the Omicron variant of SARS-CoV-2. The RBD has many mutations, which may make it more resistant to antibodies from previous infections or vaccinations. Since UDA has shown antiviral activity against SARS-CoV-2, it might be a useful drug for treating this highly transmissible variant.

Sabzian-Molaei F et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.154648

PubMed:

36681052

A novel terpenoid glycoside and other bioactive constituents from the seeds of Cichoriumintybus.

Akhtar MS et al (2023).

Carbohydr Res.

DOI:

10.1016/j.carres.2023.108745

PubMed:

36680966

Sophorolipids produced by Yarrowia lipolytica grown on Moringa oleifera oil cake protect against acetic acid-induced colitis in rats: impact on TLR-4/p-JNK/NFκB-p65 pathway.

Nooman MU et al (2023).

J Pharm Pharmacol.

DOI:

10.1093/jpp/rgac101

PubMed:

36680771

Nutritional supplement and dietary interventions as a prophylaxis or treatment of sub-concussive repetitive head impact (SRHI) and mild traumatic brain injury (mTBI): A systematic review.

Mild traumatic brain injury (mTBI) and sub-concussive repetitive head impacts (SRHIs) can cause acute and chronic symptoms. A systematic review of 15 studies on human subjects identified omega-3 fatty acids ( -3FA) as the most effective supplement for neurotrauma prevention in athletes exposed to SRHIs. Melatonin and curcumin may have benefits for persistent post-concussion symptoms. The review suggests that more multi-center studies are necessary to determine the efficacy of these supplements. Future studies should assess both novel and additional interventions examined in this review to bring more evidence to the growing field of nutritional and dietary interventions for SRHI and mTBI.

Feinberg C et al (2023).

J Neurotrauma.

DOI:

10.1089/neu.2022.0498

PubMed:

36680752

Evaluation of rooting characteristics of Ephedra cuttings by anatomy and promising strain selection based on rooting characteristics and alkaloid content.

Kudo Y et al (2023).

J Nat Med.

DOI:

10.1007/s11418-023-01680-3

PubMed:

36680565

High-quality Fagopyrum esculentum genome provides insights into the flavonoid accumulation among different tissues and self-incompatibility.

He Q et al (2023).

J Integr Plant Biol.

DOI:

10.1111/jipb.13459

PubMed:

36680412

Physicochemical and Antibacterial Properties of Alginate Films Containing Tansy (Tanacetum vulgare L.) Essential Oil.

Kowalonek J et al (2023).

Polymers (Basel).

DOI:

10.3390/polym15020260

PubMed:

36679141

Chemical Profile, Antioxidant and Anti-Inflammatory Potency of Extracts of Vitex madiensis Oliv. and Crossopteryx febrifuga (Afzel ex G. Don).

Boungou-Tsona G et al (2023).

Plants (Basel).

DOI:

10.3390/plants12020386

PubMed:

36679099