Potential of plant extracts in targeting SARS-CoV-2 main protease: an in vitro and in silico study.

Researchers at the Universidade Estadual de Maringá have discovered that an extract of [plant name], obtained by ultrasound, has a potent antiviral effect against SARS-CoV-2. In laboratory tests, the extract showed a M inhibition capacity greater than 90%, and an inhibition of 99.6% was observed in an infection model assay. Molecular docking simulations suggested that Tellimagrandin II, a component of the extract, is likely the most effective compound in inhibiting the viral enzyme. This discovery shows promise for natural compounds in the treatment of COVID-19.

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PubMed:

36651196

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Chem Biodivers.

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10.1002/cbdv.202200991

PubMed:

36650717

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J Ethnopharmacol.

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10.1016/j.jep.2023.116159

PubMed:

36649852

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Food Chem.

DOI:

10.1016/j.foodchem.2023.135463

PubMed:

36649668

Chemical Composition and Insecticidal Activity against Tribolium Castaneum of Thapsia garganica L. Seed Essential Oil.

Khemis E et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202200646

PubMed:

36649489

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Xia Y et al (2023).

Mol Biol Rep.

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10.1007/s11033-022-08237-9

PubMed:

36648695

Plants from a semi-arid environment as a source of phytochemicals against Fusarium crown and foot rot in zucchini.

Khalil AMA et al (2023).

AMB Express.

DOI:

10.1186/s13568-023-01515-0

PubMed:

36648547

A chromosome-level genome assembly of radish (Raphanus sativus L.) reveals insights into genome adaptation and differential bolting regulation.

Xu L et al (2023).

Plant Biotechnol J.

DOI:

10.1111/pbi.14011

PubMed:

36648398