Phenolic compounds in walnut pellicle improve walnut (Juglans regia L.) protein solubility under pH-shifting condition.

Kong X et al (2023).

Food Res Int.

DOI:

10.1016/j.foodres.2022.112156

PubMed:

36596107

Comparison of Two Varieties Fig (Peggy Red and Green) Peel Extracts by Liquid Chromatography-Tandem Mass Spectrometry Analysis and for Neuroprotective Efficacy in Caenorhabditis elegans.

Researchers analyzed the ethanol extract of Peggy Red and Green fig peel through LC-MS/MS to determine its phytochemical components and neuroprotective effects. They found 50 compounds including phenols, flavonoids, and anthocyanins with antioxidant properties. Peggy Red had higher antioxidant activity and was able to reduce toxicity in Alzheimer's transgenic CL4176 by decreasing the aggregation of amyloid-beta and increasing antioxidant enzyme activities. The results suggest the potential of Peggy Red peel extract as a new drug source against AD.

Liu S, Xiao C and Wang F (2023).

J Med Food.

DOI:

10.1089/jmf.2021.K.0190

PubMed:

36595373

Mechanistic Role of Methanolic Extract of Taraxacum officinale Roots as Cardioprotective Against Ischemia-Reperfusion Injury-Induced Myocardial Infarction in Rats.

Sharma M et al (2023).

Appl Biochem Biotechnol.

DOI:

10.1007/s12010-022-04282-z

PubMed:

36595191

Taxoids-rich extract from Taxus wallichiana alleviates high-fat diet-induced insulin resistance in C57BL/6 mice through inhibition of low-grade inflammation.

Binwal M et al (2023).

Inflammopharmacology.

DOI:

10.1007/s10787-022-01119-3

PubMed:

36595125

Okadaic Acid-Induced Alzheimer's in Rat Brain: Phytochemical Cucurbitacin E Contributes to Memory Gain by Reducing TAU Protein Accumulation.

Phytochemical cucurbitacin E (CuE) may be a promising drug discovery treatment in Alzheimer's disease (AD). This study investigated CuE's effects on TAU fibril formation in okadaic acid-induced AD in rats. Results suggest that CuE contributes to memory gain by reducing TAU protein accumulation. Further evaluations in future preclinical and clinical studies are warranted.

Yılmaz ŞG et al (2023).

OMICS.

DOI:

10.1089/omi.2022.0175

PubMed:

36594931

Thyme (Thymus vulgaris L.) polyphenols ameliorate DSS-induced ulcerative colitis of mice by mitigating intestinal barrier damage, regulating gut microbiota, and suppressing TLR4/NF-κB-NLRP3 inflammasome pathways.

Zhou Z et al (2023).

Food Funct.

DOI:

10.1039/d2fo02523j

PubMed:

36594593

Sodium houttuyfonate derived from Houttuynia cordata Thunb improves intestinal malfunction via maintaining gut microflora stability in Candida albicans overgrowth aggravated ulcerative colitis.

Cheng T et al (2023).

Food Funct.

DOI:

10.1039/d2fo02369e

PubMed:

36594429

6-Gingerol contents of several ginger varieties of Northeast India and correlation of their antioxidant activity in respect to phenolics and flavonoids contents.

Ghosh S et al (2023).

Phytochem Anal.

DOI:

10.1002/pca.3201

PubMed:

36594354