Photocatalytic degradation of tetracycline antibiotic and organic dyes using biogenic synthesized CuO/Fe(2)O(3) nanocomposite: pathways and mechanism insights.
- Kaushal S et al (2023).
- Environ Sci Pollut Res Int.
- PubMed:
- 36564698
Researchers synthesized four analogs of piperlongumine, an alkaloid found in Piper longum, and tested their anti-platelet aggregation activity. Compound 8 showed the strongest activity, so it was studied further and found to have good binding affinity to stroke-related protein targets. Animal experiments showed that compound 8 could significantly improve brain tissue damage after ischemia, potentially reducing injury from ischemic stroke by inhibiting apoptosis and structural disorders. This suggests piperlongumine analogs could be developed into treatments for ischemic stroke.