Ameliorative effects of nano Moringa on fluoride-induced testicular damage via down regulation of the StAR gene and altered steroid hormones.
- Abd-Allah ER and El-Rahman HAA (2023).
- Reprod Biol.
- PubMed:
- 36563520
Researchers investigated the health-promoting effects of Tibetan strawberry and identified two inhibitors that protect against neurodegenerative conditions. Using enzyme-functionalized magnetic nanoparticles coupled with UPLC-QTOF-MS, they identified quercetin-3---d-glucuronide-6″-methyl ester () and kaempferol-3---d-glucuronide-6″-methyl ester () with the IC values of 19.44 ± 1.17 and 22.63 ± 1.78 μM, respectively. Both compounds exhibited significant neuroprotective effects on 6-hydroxydopamine-induced PC12 cells. The study sheds light on the potential of functional food for developing neuroprotective compounds.
Researchers investigated using LIG, a compound derived from an herbal plant, as a potential treatment for ischemic stroke. They established an ischaemic stroke model in mice and used various tests to assess neurological deficits. Treatment with LIG showed significant anti-inflammatory and neuroprotective activity by minimizing impairment of neurological function, blocking neuronal damage, and attenuating upregulation of inflammatory cytokines. Overall, the findings suggest the potential of LIG as a treatment for stroke by inhibiting NLRP1 inflammasome and reducing inflammation.