Antidepressant-Like Activity of Solvent Fractions of the Root Bark of Carissa spinarum Linn. (Apocynaceae) in Rodents Involves Multiple Signaling Pathways.
Scientists researched the use of root bark from Linn. plants in the treatment of depression based on claims in Ethiopian folkloric medicine. They found that crude extracts of the bark had an antidepressant-like effect in rodents. This research suggests that Linn. root bark may have potential as a natural treatment for depression.
- Ali HS and Engidawork E (2022).
- J Exp Pharmacol.
- DOI:
- 10.2147/JEP.S386015
- PubMed:
- 36531440