GeoBotanical: All Studies

11441.

Mitigation of apoptosis-mediated neurotoxicity induced by silver nanoparticles via rutaceae nutraceuticals: P53 activation and Bax/Bcl-2 regulation.

Silver nanoparticles (AgNPs) are widely used in cancer treatment, but their potential neurotoxicity has not been studied. Swiss Albino mice were exposed to two sizes of AgNPs and treated with extracts from leaves, fruits, and seeds. Oxidative stress occurred after AgNP exposure, but treatment with the extracts modulated biomarkers related to apoptosis and neurotoxicity. The study suggests that AgNPs can induce neurotoxicity and genetic changes, but the extracts show promise in mitigating these effects.

Cancer Neuroscience Casimiroa edulis

Abdel-Megeed RM et al (2022).; Toxicol Rep.
DOI:: 10.1016/j.toxrep.2022.11.009
PubMed:: 36518464

11442.

Biogenic synthesis of gold nanoparticles mediated by Spondias dulcis (Anacardiaceae) peel extract and its cytotoxic activity in human breast cancer cell.

Cancer Spondias dulcis

Pechyen C et al (2022).; Toxicol Rep.
DOI:: 10.1016/j.toxrep.2022.04.031
PubMed:: 36518440

11443.

Pea eggplant (Solanum torvum Swartz) is a source of plant food polyphenols with SARS-CoV inhibiting potential.

Researchers in Malaysia investigated the potential of phytochemicals found in pea eggplant, a widely consumed vegetable, to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. The polyphenols from pea eggplant were docked with SARS-CoV receptors in molecular simulations and the best receptor-ligand complex was validated through molecular dynamics simulation. The study suggests that pea eggplant phytochemicals may have inhibitory properties against SARS-CoV-2.

COVID-19 Solanum torvum

Govender N et al (2022).; PeerJ.
DOI:: 10.7717/peerj.14168
PubMed:: 36518265

11444.

Linking genetic markers with an eco-physiological model to pyramid favourable alleles and design wheat ideotypes.

Genetics Triticum aestivum

Li Y et al (2023).; Plant Cell Environ.
DOI:: 10.1111/pce.14518
PubMed:: 36517924

11445.

Chemopreventive Effect of Cinnamon and Its Bioactive Compounds in a Rat Model of Premalignant Prostate Carcinogenesis.

Genetics Cinnamomum zeylanicum

Gopalakrishnan S et al (2023).; Cancer Prev Res (Phila).
DOI:: 10.1158/1940-6207.CAPR-22-0327
PubMed:: 36517462

11446.

Ultraviolet radiation promotes the production of hispidin polyphenols by medicinal mushroom Inonotus obliquus.

Phytochemistry Inonotus obliquus

Zhou R et al (2022).; Fungal Biol.
DOI:: 10.1016/j.funbio.2022.10.001
PubMed:: 36517145

11447.

Exploring the anti-inflammatory potential of Colocasia esculenta root extract in in-vitro and in-vivo models of inflammation.

Immunology Colocasia esculenta

Baro MR et al (2023).; J Ethnopharmacol.
DOI:: 10.1016/j.jep.2022.116021
PubMed:: 36516907

11448.

Altered microbial P cycling genes drive P availability in soil after afforestation.

Genetics Robinia pseudoacacia

Zhi R et al (2023).; J Environ Manage.
DOI:: 10.1016/j.jenvman.2022.116998
PubMed:: 36516705