All Studies

The Therapeutic Potential of Salidroside for Parkinson's Disease.

Parkinson's disease (PD) is caused by the loss of dopamine neurons in the brain, and its incidence increases with age. Salidroside is a compound found in certain plants, which has been studied for its effects on the nervous system. This review summarizes salidroside's impact on dopamine metabolism, neuronal protection, and glial activation in relation to PD. The article also describes several genes that affect PD susceptibility and the related mechanisms involving antioxidation, inflammation, and autophagy. While these studies were conducted on animals and cells, they suggest that salidroside may be a useful treatment for PD in the future.

Li L and Yao W (2023).
Planta Med.
PubMed:
36130710

PET Imaging and Neurohistochemistry Reveal that Curcumin Attenuates Brain Hypometabolism and Hippocampal Damage Induced by Status Epilepticus in Rats.

Curcumin, a compound found in turmeric, has been shown to have neuroprotective properties against neurological disorders. In this study, researchers induced seizures in rats and administered curcumin orally for 17 days. They found that curcumin reduced the number of seizures and protected the rats from brain damage caused by seizures. While curcumin did not prevent seizures or mortality, it attenuated the signs of neuronal damage and inflammation in surviving rats. These results suggest that curcumin may have adaptogen-like effects against brain damage caused by seizures.

Slowing K et al (2023).
Planta Med.
PubMed:
36130709

Saffron essential oil ameliorates CUMS-induced depression-like behavior in mice via the MAPK-CREB1-BDNF signaling pathway.

Saffron has been traditionally used in Chinese and Islamic medicine to treat depression, and its aroma is known to have calming effects. Researchers studied the composition of saffron's volatile oil and found that it has properties that could potentially help with depression and anxiety. This suggests that saffron may have therapeutic benefits beyond its traditional use as a spice.

Chen Z et al (2023).
J Ethnopharmacol.
PubMed:
36126781