The Therapeutic Potential of Salidroside for Parkinson's Disease.
Parkinson's disease (PD) is caused by the loss of dopamine neurons in the brain, and its incidence increases with age. Salidroside is a compound found in certain plants, which has been studied for its effects on the nervous system. This review summarizes salidroside's impact on dopamine metabolism, neuronal protection, and glial activation in relation to PD. The article also describes several genes that affect PD susceptibility and the related mechanisms involving antioxidation, inflammation, and autophagy. While these studies were conducted on animals and cells, they suggest that salidroside may be a useful treatment for PD in the future.
- Li L and Yao W (2023).
- Planta Med.
- DOI:
- 10.1055/a-1948-3179
- PubMed:
- 36130710