Pseudolycorine chloride ameliorates Th17 cell-mediated central nervous system autoimmunity by restraining myeloid-derived suppressor cell expansion.
Researchers investigated the immunopharmacological effects of pseudolycorine chloride (PLY), a constituent of L. var. Roem with antitumor and antiviral activities. They found that PLY significantly increased the production of cytokines and chemokines, indicating its potential in modulating the immune response. This study sheds light on the potential medical uses of PLY as an immunomodulator.
- Zhang G et al (2022).
- Pharm Biol.
- PubMed:
- 36082828