Structural elucidation and anti-neuroinflammatory activity of Polygala tenuifolia polysaccharide.
- Zeng Z et al (2022).
- Int J Biol Macromol.
- PubMed:
- 36037912
Researchers isolated nine coumarins from the Sarcandra glabra plant, including a newly discovered pair of enantiomers. They tested all the compounds for acetylcholinesterase inhibiting activity and found that compound 3 showed the most significant effect with an IC value of 1.982±0.003 μM. The study confirms the potential therapeutic properties of coumarins and its ability to target Alzheimer's disease.