All Studies

[Exploration on mechanism of Polygalae Radix and Acori Tatarinowii Rhizoma in treating Alzheimer's disease based on network pharmacology and experimental verification].

Scientists used network pharmacology, molecular docking, and animal tests to investigate the effects of Polygala tenuifolia and Acorus tatarinowii in treating Alzheimer's disease (AD). By analyzing active ingredients and targets of the traditional Chinese medicines, they identified core targets and pathways involved in AD. Mice with cognitive impairment were given the treatments, which improved learning and memory abilities and reduced neuron damage. The results suggest that P. tenuifolia and A. tatarinowii have potential for treating AD through multiple components, targets, and pathways.

Su SJ et al (2022).
Zhongguo Zhong Yao Za Zhi.
PubMed:
35851129