In Silico Studies on Zinc Oxide Based Nanostructured Oil Carriers with Seed Extracts of Nigella sativa and Pimpinella anisum as Potential Inhibitors of 3CL Protease of SARS-CoV-2.

Scientists synthesized zinc oxide nanoparticles using olive and black seed essential oils and investigated 27 bioactive compounds, including ZnO, as potential inhibitors for the SARS-CoV-2 main protease. The study optimized dithymoquinone, δ-hederin, oleuropein, and ZnO, which showed promising results in molecular docking studies and molecular dynamics simulations. Further experimental validation of these compounds is required before considering them for clinical trials as a potent inhibitor of COVID-19.

Hendi AA et al (2022).

Molecules.

DOI:

10.3390/molecules27134301

PubMed:

35807545

Origanum syriacum Phytochemistry and Pharmacological Properties: A Comprehensive Review.

Mesmar J et al (2022).

Molecules.

DOI:

10.3390/molecules27134272

PubMed:

35807517

Phytochemical Investigation of Cordia africana Lam. Stem Bark: Molecular Simulation Approach.

Sabry MM et al (2022).

Molecules.

DOI:

10.3390/molecules27134039

PubMed:

35807285

(-)-α-Bisabolol Alleviates Atopic Dermatitis by Inhibiting MAPK and NF-κB Signaling in Mast Cell.

Li G et al (2022).

Molecules.

DOI:

10.3390/molecules27133985

PubMed:

35807237

Preliminary Study of the Antimicrobial, Anticoagulant, Antioxidant, Cytotoxic, and Anti-Inflammatory Activity of Five Selected Plants with Therapeutic Application in Dentistry.

López Villarreal SM et al (2022).

Int J Environ Res Public Health.

DOI:

10.3390/ijerph19137927

PubMed:

35805583

Anti-Inflammatory Food in Asthma Prepared from Combination of Raphanus sativus L., Allium hookeri, Acanthopanax sessiliflorum, and Dendropanax morbiferus Extracts via Bioassay-Guided Selection.

Researchers studied herbal plant extracts to create a nutraceutical that improves immune response to air pollutants, reducing inflammation in asthma. Their product successfully inhibited inflammatory cytokines in rat models, showing potential as a functional food for asthma treatment.

Lee KD and Shim SY (2022).

Foods.

DOI:

10.3390/foods11131910

PubMed:

35804727

Structure Characterization, Antioxidant and Immunomodulatory Activities of Polysaccharide from Pteridium aquilinum (L.) Kuhn.

Zhao ZH et al (2022).

Foods.

DOI:

10.3390/foods11131834

PubMed:

35804650

Effect of Hydrothermal Cooking and Germination Treatment on Functional and Physicochemical Properties of Parkia timoriana Bean Flours: An Underexplored Legume Species of Parkia Genera.

Medhe SV et al (2022).

Foods.

DOI:

10.3390/foods11131822

PubMed:

35804637