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Mucuna pruriens Seed Aqueous Extract Improved Neuroprotective and Acetylcholinesterase Inhibitory Effects Compared with Synthetic L-Dopa.

The study investigated the use of a traditional Ayurvedic medicine, Mucuna pruriens, as an anti-Parkinson's agent due to the toxicity of current treatment options. The study found that the seed extract showed significant neuroprotective properties and inhibitory activity against acetylcholinesterase, a target in treating Parkinson's disease. The extract containing L-dopa was found to have a superior benefit compared to synthetic L-dopa. This implies that the administration of the seed extract may be a promising treatment option for neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.

Kamkaen N et al (2022).
Molecules.
PubMed:
35630617