Breaking the limits - multichromosomal structure of an early eudicot Pulsatilla patens mitogenome reveals extensive RNA-editing, longest repeats and chloroplast derived regions among sequenced land plant mitogenomes.

Szandar K et al (2022).

BMC Plant Biol.

DOI:

10.1186/s12870-022-03492-1

PubMed:

35264098

Ethanolic Extract of Tridax procumbens Mitigates Pulmonary Inflammation via Inhibition of NF-κB/p65/ERK Mediated Signalling in an Allergic Asthma Model.

Tridax procumbens is a medicinal plant with anti-inflammatory properties. It effectively reduces oxidative stress and inflammation, but its impact on allergic asthma remains unclear.

Devi K et al (2022).

Phytomedicine.

DOI:

10.1016/j.phymed.2022.154008

PubMed:

35263673

Sesquiterpene lactones from Xanthium sibiricum Patrin alleviate asthma by modulating the Th1/Th2 balance in a murine model.

Scientists studied compound SL-XS from X. sibiricum, a traditional Chinese medicine, for its anti-asthma effects. Understanding its bioactive properties may lead to new treatments for asthma.

Han J et al (2022).

Phytomedicine.

DOI:

10.1016/j.phymed.2022.154032

PubMed:

35263672

Antimicrobial potential of plant extracts from the Brazilian Cerrado.

Volpato LER et al (2022).

Braz Dent J.

DOI:

10.1590/0103-6440202204705

PubMed:

35262558

Garlic (Allium sativum Linnaeus) improved inflammation and reduced cryptosporidiosis burden in immunocompromised mice.

Farid A, Yousry M and Safwat G (2022).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115174

PubMed:

35259443

A review on the ethnopharmacology, phytochemistry and pharmacology of Polygonum hydropiper Linn.

Bairagi J et al (2022).

J Pharm Pharmacol.

DOI:

10.1093/jpp/rgab175

PubMed:

35259273

In silico and in vitro studies on inhibitors for SARS-CoV-2 non-structural proteins with dual herbal combination of Withania somnifera with five rasayana herbs.

A study investigated the potential of dual herbal extracts for their ability to bind to COVID-19 nonstructural proteins (nsp) and to counteract external stimulus. The combination of extracts W and P showed remarkable docking scores and high binding energy for nsp. The extracts also yielded levels of interferon alpha in cell lines to establish an antiviral state. The study suggests that nsp can be targeted with effective antiviral drugs to combat viral RNA synthesis and suppression of host immunity.

Bhargavi S, Madhan Shankar SR and Jemmy CH (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2022.2046642

PubMed:

35257637

Network pharmacology analysis reveals neuroprotection of Gynostemma pentaphyllum (Thunb.) Makino in Alzheimer' disease.

Chinese medicinal herb Gynostemma Pentaphyllum (Thunb.) Makino (GpM) has been reported to ameliorate cognitive impairment in Alzheimer's disease (AD), but its neuroprotective mechanism remains unclear. Researchers aimed to investigate the targets and possible signaling pathways of GpM in the treatment of AD. GpM's anti-inflammatory, anti-oxidative stress, and anti-tumor properties make it a promising candidate for AD drug treatment.

Wang J et al (2022).

BMC Complement Med Ther.

DOI:

10.1186/s12906-022-03534-z

PubMed:

35255879