All Studies

Scolymus hispanicus (Golden Thistle) Ameliorates Hepatic Steatosis and Metabolic Syndrome by Reducing Lipid Accumulation, Oxidative Stress, and Inflammation in Rats under Hyperfatty Diet.

Berdja S et al (2021).
Evid Based Complement Alternat Med.
PubMed:
34335826

Flavonoids in Ampelopsis grossedentata as covalent inhibitors of SARS-CoV-2 3CL(pro): Inhibition potentials, covalent binding sites and inhibitory mechanisms.

Researchers identified the key constituents in Ampelopsis grossedentata extract (AGE) responsible for inhibiting coronavirus 3C-like protease (3CL), a target for treating COVID-19. Flavonoid-rich fractions from AGE were found to strongly inhibit SARS-CoV-2-3CL, with dihydromyricetin, isodihydromyricetin, and myricetin identified as the most effective compounds. The researchers found that myricetin covalently binds to SARS-CoV-2-3CL at Cys300 and Cys44, while dihydromyricetin and isodihydromyricetin covalently bind at Cys300, suggesting that these compounds could be used to develop new antiviral agents.

Xiong Y et al (2021).
Int J Biol Macromol.
PubMed:
34333006

Characterization of essential oils and volatiles from the aerial parts of Mentha pulegium L. (Lamiaceae) using microwave-assisted hydrodistillation (MAHD) and headspace solid phase microextraction (HS-SPME) in combination with GC-MS.

Mohammadhosseini M, Venditti A and Mahdavi B (2023).
Nat Prod Res.
PubMed:
34328036

Recombinant production of Trx-Ib-AMP4 and Trx-E50-52 antimicrobial peptides and antimicrobial synergistic assessment on the treatment of methicillin-resistant Staphylococcus aureus under in vitro and in vivo situations.

Satei P et al (2021).
Protein Expr Purif.
PubMed:
34324967