Untargeted metabolomics revealed the mechanism of aucubin on glucocorticoid-induced osteoporosis in mice through modulating arachidonic acid metabolism.
- Wang H et al (2024).
- J Pharm Biomed Anal.
- PubMed:
- 38878451
Researchers studied chemoresistance in colorectal cancer cells treated with 5-FU, finding various resistance mechanisms. Curcumin and piperine enhance 5-FU sensitivity, showing promise for improving chemotherapy effectiveness.
Researchers developed a new antibacterial agent, BcN16E, that effectively treats infections in zebrafish by damaging bacterial membranes and boosting immune response. This novel complex shows promise for future medical use in combating antibiotic resistance.