All Studies

Schisandra chinensis lignans improve insulin resistance by targeting TLR4 and activating IRS-1/PI3K/AKT and NF-κB signaling pathways.

Schisandra chinensis compounds 2 and 4 improve insulin resistance by targeting TLR4, modulating NF-κB and IRS-1/PI3K/AKT pathways, offering potential as T2DM treatments.

ImmunologyPhytochemistry Schisandra chinensis
Zhao SL et al (2024).
Int Immunopharmacol.
DOI:
10.1016/j.intimp.2024.113069
PubMed:
39241520

Rapid determination of phenolic composition in chamomile (Matricaria recutita L.) using surface-enhanced Raman spectroscopy.

Study used SERS to quickly analyze polyphenols in chamomile. SERS a cheaper, faster alternative to traditional methods. Useful for analyzing antioxidant components in herbal teas efficiently.

Phytochemistry Matricaria recutita
de Angelis M et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.141084
PubMed:
39241429

Tailored NADES solvents for the extraction optimization of benzylisoquinoline alkaloids from Thalictrum foliolosum DC.- A potential phyto-nutraceutical source.

Researchers optimized extraction of alkaloids from Thalictrum foliolosum DC using tailor-made deep eutectic solvents and ultrasonication. The method yielded high amounts of berberine, berbamine, magnoflorine, and palmatine with strong antioxidant and anti-glycemic properties, suitable for pharmaceutical and nutraceutical industries.

Phytochemistry Thalictrum foliolosum
Singh B et al (2024).
Food Chem.
DOI:
10.1016/j.foodchem.2024.141016
PubMed:
39241417

Efficient enrichment and characterization of triterpenoid saponins from Platycodon grandiflorus roots.

Study optimized extraction and purification of triterpenoid saponins from Platycodon grandiflorum roots for pharmaceutical potential. Results show increased content and variations in compounds, supporting future drug development.

Phytochemistry Platycodon grandiflorus
Li W et al (2024).
J Chromatogr A.
DOI:
10.1016/j.chroma.2024.465332
PubMed:
39241405

Dehydroevodiamine targeting IKKβ to alleviate acute gastric injury via inhibiting the p65/NLRP3 axis.

DHE from Tetradium ruticarpum may help treat acute gastric injury by studying its mechanisms. This could improve patient quality of life and overall health.

Gastroenterology Tetradium ruticarpum
Hu Q et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.155963
PubMed:
39241388

Potential of 6'‑hydroxy justicidin B from Justicia procumbens as a therapeutic agent against coronavirus disease 2019.

Researchers have discovered a potential antiviral compound, 6'-HJB, from a traditional Chinese medicine plant, which may be effective against COVID-19 and its variants. This could provide new therapeutic options in addition to vaccines.

COVID-19 Justicia procumbens
Yoo MH et al (2024).
Phytomedicine.
DOI:
10.1016/j.phymed.2024.156014
PubMed:
39241386

Expression patterns of candidate genes for the Lr46/Yr29 "slow rust" locus in common wheat (Triticum aestivum L.) and associated miRNAs inform of the gene conferring the Puccinia triticina resistance trait.

Researchers analyzed expression of candidate genes at Lr46/Yr29 locus in wheat resistant to leaf rust caused by Pt. Identified gene Lr46-Glu2 may play role in resistance response. This study provides insight for developing disease-resistant wheat varieties.

Genetics Triticum aestivum
Spychała J et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0309944
PubMed:
39240941

Genetic drift, historic migration, and limited gene flow contributing to the subpopulation divergence in wild sea beet (Beta vulgaris ssp. maritima (L.) Arcang).

Scientists analyzed sea beet accessions to understand evolution and genetic diversity. Sea beet originated in southern Europe and dispersed through marine currents to form subpopulations. This research aids in conserving and utilizing sea beet for sugarbeet improvement.

Genetics Beta vulgaris
Tehseen MM et al (2024).
PLoS One.
DOI:
10.1371/journal.pone.0308626
PubMed:
39240839
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