All Studies

Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.

- AKI involves kidney function decline due to inflammation - PF11 from plant modulates macrophage function - Protects kidney cells and reduces inflammation in mouse model - Potential treatment for AKI by regulating macrophages

Immunology Panax quinquefolius
Wang Y et al (2024).
J Agric Food Chem.
DOI:
10.1021/acs.jafc.4c05185
PubMed:
39239930

Microbial Biotransformation of 1-Methyl-L-tryptophan into Herbicidal Indole Alkaloids by Endophytic Fungus Nigrospora chinensis GGY-3.

GGY-3 transformed 1-MT into new and known indole alkaloids using a Friedel-Crafts reaction. Some compounds showed strong herbicidal activity on dicotyledon weeds, comparable to penoxsulam.

Phytochemistry Eclipta prostrata
Wang B et al (2024).
J Org Chem.
DOI:
10.1021/acs.joc.4c01514
PubMed:
39239664

Alkaloids in Chelidonium majus L: a review of its phytochemistry, pharmacology and toxicology.

Researchers studied the alkaloids in L. plant, known for its medicinal properties. These alkaloids have various pharmacological effects including anti-microbial and anti-inflammatory properties. This review provides a basis for using L. in medicinal chemistry research.

Phytochemistry Chelidonium majus
Li XL et al (2024).
Front Pharmacol.
DOI:
10.3389/fphar.2024.1440979
PubMed:
39239653

Phenotyping data coupled with RNA sequencing of apple genotypes exhibiting contrasted quantitative trait loci architecture for apple scab (Venturia inaequalis) resistance.

Scientists studied three QTLs in apple resistance to scab, using RNA sequencing to identify candidate genes. This research can lead to improved apple breeding strategies for better scab resistance.

Genetics Malus domestica
Bénéjam J et al (2024).
Data Brief.
DOI:
10.1016/j.dib.2024.110778
PubMed:
39239265

Study on chemical constituents and antioxidant activities of Dianthus caryophyllus L.

Study evaluated antioxidant and antitumor properties of carnation plant extracts using metabolomics. Important for potential medicinal and ornamental value.

Immunology Dianthus caryophyllus
Wang M et al (2024).
Front Plant Sci.
DOI:
10.3389/fpls.2024.1438967
PubMed:
39239204

Cocos nucifera and glycerine afterwork moisturizers for secondary prevention of hand dermatitis among fabric worker: a randomized, double-blind, cross over trial.

Study found that coconut oil and glycerin cream equally effective in preventing hand dermatitis for batik workers. Decreased HECSI and TEWL, increased skin hydration. Use for skin barrier protection.

Dermatology Cocos nucifera
Budianti WK et al (2024).
Sci Rep.
DOI:
10.1038/s41598-024-72010-0
PubMed:
39237662

Amoebicidal activity of essential oils and essential oil-based microemulsions of Aloysia citrodora Ortega ex Pers., Cymbopogon winterianus Jowitt ex Bor and Ocimum gratissimum L. against Acanthamoeba polyphaga trophozoites.

Essential oils from Aloysia citrodora, Cymbopogon winterianus, and Ocimum gratissimum showed potential in killing Acanthamoeba polyphaga. Microemulsions with these oils were effective. Relevant for potential anti-amoebic treatments.

Phytochemistry Ocimum gratissimum
Siqueira IB et al (2024).
J Appl Microbiol.
DOI:
10.1093/jambio/lxae232
PubMed:
39237458

Piperlongumine, a natural alkaloid from Piper longum L. ameliorates metabolic-associated fatty liver disease by antagonizing the thromboxane A(2) receptor.

TL;DR: Piperlongumine (PL) from Piper longum L. fruits improved MAFLD in mice by reducing hepatic gluconeogenesis, lipogenesis, and insulin resistance. PL targets CRTC2, CREB, and Srebp-1c, and antagonizes TP receptor to combat MAFLD induced by HFD. Potential therapeutic strategy.

Phytochemistry Piper longum
Dai Y et al (2024).
Biochem Pharmacol.
DOI:
10.1016/j.bcp.2024.116518
PubMed:
39236933
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