New isoflavone glucosides in yabumame (Amphicarpaea bracteata (L.) Fernald subsp. edgeworthii (Benth.) H.Ohashi var. japonica (Oliv.) H.Ohashi) and their effect on leukotriene B(4) production in mast cells.

Yang L et al (2021).

J Nat Med.

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10.1007/s11418-020-01439-0

PubMed:

32803653

Acteoside Isolated from Colebrookea oppositifolia Smith Attenuates Epilepsy in Mice Via Modulation of Gamma-Aminobutyric Acid Pathways.

Acteoside was evaluated for its anticonvulsant properties and mechanism of action in mice. It was found to have significant anticonvulsant activity in the pentylenetetrazole (PTZ) model, but not in the maximal electroshock (MES) or N-methyl-D-aspartic acid (NMDA) models. Studies on the PTZ model showed that acteoside restored altered antioxidant levels, GABA mRNA levels, and glutamate levels in the cortex and hippocampus regions of PTZ-treated mice. The anticonvulsant activity of acteoside was confirmed to be due to its GABAergic mechanism and was found to have no central side effects. The study concludes that acteoside and related compounds may be useful in the treatment of epilepsy.

Viswanatha GL et al (2020).

Neurotox Res.

DOI:

10.1007/s12640-020-00267-0

PubMed:

32803629

Screening of optimal reference genes for qRT-PCR and preliminary exploration of cold resistance mechanisms in Prunus mume and Prunus sibirica varieties.

Ding A et al (2020).

Mol Biol Rep.

DOI:

10.1007/s11033-020-05714-x

PubMed:

32803506

Urtica Pilulifera in Treating Pre-diabetic Rat Model to Control the Blood Glucose, Lipids and Oxidative Stress.

Amawi KF and Alkhatib AJ (2020).

Med Arch.

DOI:

10.5455/medarh.2020.74.168-171

PubMed:

32801429

Lophatherum gracile Brongn. attenuates neutrophilic inflammation through inhibition of JNK and calcium.

Lai KH et al (2021).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2020.113224

PubMed:

32800928

Novel potent natural peroxidases inhibitors with in vitro assays, inhibition mechanism and molecular docking of phenolic compounds and alkaloids.

Benarous K et al (2021).

J Biomol Struct Dyn.

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10.1080/07391102.2020.1808073

PubMed:

32799732

Compound-specific responses of phenolic metabolites in the bark of drought-stressed Salix daphnoides and Salix purpurea.

Köhler A et al (2020).

Plant Physiol Biochem.

DOI:

10.1016/j.plaphy.2020.07.004

PubMed:

32798899

Pinellia ternata (Thunb.) Breit: A review of its germplasm resources, genetic diversity and active components.

Mao R and He Z (2020).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2020.113252

PubMed:

32798614