Integrated network pharmacology and pharmacological investigations to discover the active compounds of Toona sinensis pericarps against diabetic nephropathy.

Toona sinensis plant has medicinal properties for treating diabetes, kidney disease, inflammation, and oxidative stress. Consider studying its potential benefits for scientific research in the lab.

Li H et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.118441

PubMed:

38851471

Combined dynamic transcriptome and flavonoid metabolome reveal the role of Mo nanoparticles in the nodulation process in soybean.

Liu Y et al (2024).

Sci Total Environ.

DOI:

10.1016/j.scitotenv.2024.173733

PubMed:

38851347

Tetrastigma hemsleyanum polysaccharide ameliorated ulcerative colitis by remodeling intestinal mucosal barrier function via regulating the SOCS1/JAK2/STAT3 pathway.

Bao X et al (2024).

Int Immunopharmacol.

DOI:

10.1016/j.intimp.2024.112404

PubMed:

38851163

Fagopyrum Dibotrys Rhizoma regulates pulmonary lipid metabolic homeostasis and the ERK-cPLA(2) pathway to alleviate asthma in mice.

FDR, a traditional Chinese medicine, shows promise in treating asthma by targeting multiple factors with low side effects. Further research needed for exact mechanism.

Wang X et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155782

PubMed:

38851102

Total saponins from Panax japonicus regulated the intestinal microbiota to alleviate lipid metabolism disorders in aging mice.

Hu Y et al (2024).

Arch Gerontol Geriatr.

DOI:

10.1016/j.archger.2024.105500

PubMed:

38851092

Potential anti-liver cancer targets and mechanisms of kaempferitrin based on network pharmacology, molecular docking and experimental verification.

Kaempferitrin in Chenopodium ambrosioides fights liver cancer by targeting specific pathways, verified in mice models. Important for developing treatments for liver cancer.

Zhou S et al (2024).

Comput Biol Med.

DOI:

10.1016/j.compbiomed.2024.108693

PubMed:

38850960

Investigating the proliferative inhibition of HepG2 cells by exosome-like nanovesicles derived from Centella asiatica extract through metabolomics.

Researchers created Centella asiatica-derived nanovesicles (ADNVs) with anticancer properties through a simple process. ADNVs target diseases like cancer, show internalization in HepG2 cells, and impact metabolic pathways, suggesting their potential as effective anticancer agents.

Huang J et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116855

PubMed:

38850651

Research of the dynamic regulatory mechanism of Compound Danshen Dripping Pills on myocardial infarction based on metabolic trajectory analysis.

Tossers studied CDDP for MI treatment, but focused on endpoints, neglecting dynamic changes in disease. Establishing dynamic research strategy for precise clinical medication guidance is crucial.

Zhang CJ et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155626

PubMed:

38850631