All Studies

Inhibition of acetylcholinesterase by extracts and constituents from Angelica archangelica and Geranium sylvaticum.

This study investigated the ability of Icelandic medicinal herbs to inhibit acetylcholinesterase (AChE). Two extracts, Angelica archangelica seeds and Geranium sylvaticum aerial parts, were effective in inhibiting AChE. Xanthotoxin from A. archangelica was more potent than imperatorin. However, furanocoumarins likely played a minor role in the extract's total activity. A synergistic effect was observed when the extracts of A. archangelica and G. sylvaticum were combined. Other medicinal herbs did not show AChE inhibitory activity. This research highlights the potential of these specific Icelandic herbs for developing treatments for disorders associated with AChE inhibition, such as Alzheimer's disease.

Sigurdsson S and Gudbjarnason S (2007).
Z Naturforsch C J Biosci.
PubMed:
18069242

Analgesic, anti-inflammatory and hypoglycaemic effects of Securidaca longepedunculata (Fresen.) [Polygalaceae] root-bark aqueous extract.

Ojewole JA et al (2008).
Inflammopharmacology.
PubMed:
18046514

Studies on the chemical constituents and anticancer activity of Saxifraga stolonifera (L) Meeb.

Chen Z et al (2008).
Bioorg Med Chem.
PubMed:
17997321

Simultaneous determination of active ingredients in ethnomedicine Gaultheria leucocarpa var. yunnanensis and its medicinal preparation by capillary electrophoresis with electrochemical detection.

Zeng Y et al (2007).
J Chromatogr Sci.
PubMed:
17988450