[On the saponin of Hepatica triloba Chaix].
- GARCIA MARQUINA JM and GALLARDO VILLA M (1948).
- Farmacognosia.
- PubMed:
- 18107063
This study investigated the ability of Icelandic medicinal herbs to inhibit acetylcholinesterase (AChE). Two extracts, Angelica archangelica seeds and Geranium sylvaticum aerial parts, were effective in inhibiting AChE. Xanthotoxin from A. archangelica was more potent than imperatorin. However, furanocoumarins likely played a minor role in the extract's total activity. A synergistic effect was observed when the extracts of A. archangelica and G. sylvaticum were combined. Other medicinal herbs did not show AChE inhibitory activity. This research highlights the potential of these specific Icelandic herbs for developing treatments for disorders associated with AChE inhibition, such as Alzheimer's disease.