Positive regulation of the Eucommia rubber biosynthesis-related gene EuFPS1 by EuWRKY30 in Eucommia ulmoides.

Zhang S et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.131751

PubMed:

38657917

Anti-pancreatic cancer activity of cassane diterpenoids isolated from the seeds of Caesalpinia sappan mediated by autophagy activation via ROS/AMPK/mTORC1 pathway.

Researchers isolated new cassane diterpenoids from Caesalpinia sappan seeds. Compound 4 showed anti-cancer activity against pancreatic cancer cells by inducing autophagy through the ROS/AMPK/mTORC1 pathway. This suggests potential for 4 as a therapy for pancreatic cancer.

Su J et al (2024).

Phytochemistry.

DOI:

10.1016/j.phytochem.2024.114105

PubMed:

38657886

Microencapsulation of ginger essential oil using mung bean protein isolate-chitosan complex coacervates: Application in the preservation of crab meatballs and the prediction of shelf life.

Shen J, Zhang M and Yang C (2024).

Food Chem.

DOI:

10.1016/j.foodchem.2024.139263

PubMed:

38657553

Combined untargeted metabolomics and network pharmacology approaches to reveal the therapeutic role of withanolide B in psoriasis.

Li T et al (2024).

J Pharm Biomed Anal.

DOI:

10.1016/j.jpba.2024.116163

PubMed:

38657365

Elucidating the anti-obesity potential of bioactive fractions of kalanchoe pinnata (lam.) leaves extract using a combination of in vitro, in vivo and in silico methods along with characterisation of lead compounds through an HPTLC ms-MS(n) analytical study.

Scientists isolated and tested anti-obesity fractions from leaves. Fraction F2 showed the most potential, reducing body weight and lipids in obese mice. It contains compounds with binding capability for proteins, suggesting a therapeutic strategy for obesity.

Pratap Singh R and Pattnaik AK (2024).

Nat Prod Res.

DOI:

10.1080/14786419.2024.2344183

PubMed:

38656916

Scutellarin ameliorates diabetic nephropathy via TGF-β1 signaling pathway.

Scutellarin from breviscapine improves diabetic nephropathy by reducing proteinuria, glomerular expansion, and renal fibrosis. Works through TGF-β1, Erk, and Wnt/β-catenin pathways. Important for treating DN.

Huang B et al (2024).

Nat Prod Bioprospect.

DOI:

10.1007/s13659-024-00446-y

PubMed:

38656633

Integrated spatial metabolomics and transcriptomics decipher the hepatoprotection mechanisms of wedelolactone and demethylwedelolactone on non-alcoholic fatty liver disease.

Chen P et al (2024).

J Pharm Anal.

DOI:

10.1016/j.jpha.2023.11.017

PubMed:

38655398

Exploring the neuroprotection of the combination of astragaloside A, chlorogenic acid and scutellarin in treating chronic cerebral ischemia via network analysis and experimental validation.

The combination of Astragalus and Salvia extracts can help improve cognitive function and neurological impairments in chronic cerebral ischemia by activating the PI3K/AKT pathway, offering potential as a therapeutic medication.

Cheng F et al (2024).

Heliyon.

DOI:

10.1016/j.heliyon.2024.e29162

PubMed:

38655299